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TGFA protein, human

Known as: TGF-Alpha, Epidermal Growth Factor Related Transforming Growth Factor, Transforming Growth Factor, Alpha 
Transforming growth factor alpha (50 aa, ~6 kDa) is encoded by the human TGFA gene. This protein is involved in both epidermal growth factor receptor… 
National Institutes of Health

Related topics

Related topics

10 relations
Cell Proliferation Regulatory ProcessERBB Family Signaling PathwayEsophageal carcinomaExtracellular Space

Broader (1)

Transforming Growth Factor alpha

Papers overview

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Highly Cited
2004
Highly Cited
2004
Clonogenicity of Human Endometrial Epithelial and Stromal Cells1
Abstract The human endometrium regenerates from the lower basalis layer, a germinal compartment that persists after menstruation… 
Highly Cited
2002
Highly Cited
2002
Monoclonal antibodies to target epidermal growth factor receptor–positive tumors
Traditional cytotoxic approaches to tumor management are associated with efficacy and toxicity limitations. Blockade of the… 
Highly Cited
2001
Highly Cited
2001
Effects of epigallocatechin-3-gallate on growth, epidermal growth factor receptor signaling pathways, gene expression, and chemosensitivity in human head and neck squamous cell carcinoma cell lines.
The antitumor effects of the green tea compound epigallocatechin-3-gallate (EGCG) have not been studied in detail previously in… 
Highly Cited
1996
Highly Cited
1996
Population expansion, clonal growth, and specific differentiation patterns in primary cultures of hepatocytes induced by HGF/SF, EGF and TGF alpha in a chemically defined (HGM) medium
Mature adult parenchymal hepatocytes, typically of restricted capacity to proliferate in culture, can now enter into clonal… 
Highly Cited
1996
Highly Cited
1996
Orofacial clefts, parental cigarette smoking, and transforming growth factor-alpha gene variants.
Results of studies to determine whether women who smoke during early pregnancy are at increased risk of delivering infants with… 
Highly Cited
1989
Highly Cited
1989
Structure and function of human amphiregulin: a member of the epidermal growth factor family.
The complete amino acid sequence of amphiregulin, a bifunctional cell growth modulator, was determined. The truncated form… 
Highly Cited
1989
Highly Cited
1989
Endothelin is a potent mitogen for rat vascular smooth muscle cells.
Highly Cited
1988
Highly Cited
1988
Expression of messenger RNAs for platelet-derived growth factor and transforming growth factor-alpha and their receptors in human malignant glioma cell lines.
Formal proof for an involvement of autocrine stimulation in the disturbed growth of malignant cells has been difficult to obtain… 
Highly Cited
1987
Highly Cited
1987
Epithelial wound healing enhanced by transforming growth factor-alpha and vaccinia growth factor.
Epidermal regeneration following middermal injuries to skin requires both proliferation and migration of keratinocytes. Epidermal… 
Highly Cited
1986
Highly Cited
1986
Transforming growth factor-alpha: a more potent angiogenic mediator than epidermal growth factor.
Transforming growth factor-alpha (TGF-alpha) and epidermal growth factor (EGF) are structurally related peptides. Purified human… 
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