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TFPI gene

Known as: LIPOPROTEIN-ASSOCIATED COAGULATION INHIBITOR, TFPI1, EXTRINSIC PATHWAY INHIBITOR 
This gene plays a role in blood coagulation.
National Institutes of Health

Related topics

Related topics

5 relations
Protein Degradation InhibitionRegulation of ProteolysisTissue Factor Pathway Inhibitor, humanTissue factor pathway inhibitor

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TFPI wt Allele

Papers overview

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Highly Cited
2002
Highly Cited
2002
Lethal Perinatal Thrombosis in Mice Resulting From the Interaction of Tissue Factor Pathway Inhibitor Deficiency and Factor V Leiden
Background—Factor V Leiden (FVL) is a common genetic risk factor for thrombosis in humans. The incomplete penetrance of FVL… 
Highly Cited
1999
Highly Cited
1999
TFPIβ, a Second Product from the Mouse Tissue Factor Pathway Inhibitor (TFPI) Gene
Summary Tissue factor pathway inhibitor (TFPI) contains three Kunitz domains separated by two connecting regions. We have cloned… 
Highly Cited
1995
Highly Cited
1995
An anti-tissue factor pathway inhibitor (TFPI) monoclonal antibody recognized the third Kunitz domain (K3) of free-form TFPI but not lipoprotein-associated forms in plasma.
Tissue factor pathway inhibitor (TFPI) is a Kunitz-type protease inhibitor with three tandem inhibitory domains, which inhibits… 
Highly Cited
1993
Highly Cited
1993
The functional expression of tissue factor by fibroblasts and endothelial cells under flow conditions.
The expression of tissue factor (TF) by a variety of vascular cell types under physiologic flow conditions is critical to factor… 
Highly Cited
1993
Highly Cited
1993
Evidence that the C-terminus of tissue factor pathway inhibitor (TFPI) is essential for its in vitro and in vivo interaction with lipoproteins.
We have previously shown that the C-terminus of TFPI is essential for its anticoagulant activity. In the present study we have… 
Highly Cited
1990
Highly Cited
1990
Recombinant human extrinsic pathway inhibitor. Production, isolation, and characterization of its inhibitory activity on tissue factor-initiated coagulation reactions.
Highly Cited
1989
Highly Cited
1989
Human plasma extrinsic pathway inhibitor activity: I. Standardization of assay and evaluation of physiologic variables.
An assay was standardized to measure extrinsic pathway inhibitor (EPI) activity in human plasma. Variables that could potentially… 
Highly Cited
1989
Highly Cited
1989
Factor VII and extrinsic pathway inhibitor in acute coronary disease
Summary. This report describes studies on the activation of coagulation factor VII (FVII) and the inhibition of the extrinsic… 
Highly Cited
1989
Highly Cited
1989
Extrinsic pathway inhibitor in postoperative/posttraumatic septicemia: increased levels in fatal cases.
The activity of the extrinsic pathway inhibitor (EPI), which is the factor-Xa-dependent inhibitor of the factor VIIa-tissue… 
1989
1989
Human plasma extrinsic pathway inhibitor activity: II. Plasma levels in disseminated intravascular coagulation and hepatocellular disease.
Plasma or serum extrinsic pathway inhibitor (EPI) activity was measured in 24 patients with disseminated intravascular… 
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