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TFPI gene
Known as:
LIPOPROTEIN-ASSOCIATED COAGULATION INHIBITOR
, TFPI1
, EXTRINSIC PATHWAY INHIBITOR
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This gene plays a role in blood coagulation.
National Institutes of Health
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Related topics
Related topics
5 relations
Protein Degradation Inhibition
Regulation of Proteolysis
Tissue Factor Pathway Inhibitor, human
Tissue factor pathway inhibitor
Narrower (1)
TFPI wt Allele
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2002
Highly Cited
2002
Lethal Perinatal Thrombosis in Mice Resulting From the Interaction of Tissue Factor Pathway Inhibitor Deficiency and Factor V Leiden
D. Eitzman
,
R. Westrick
,
+4 authors
D. Ginsburg
Circulation
2002
Corpus ID: 1886268
Background—Factor V Leiden (FVL) is a common genetic risk factor for thrombosis in humans. The incomplete penetrance of FVL…
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Highly Cited
1999
Highly Cited
1999
TFPIβ, a Second Product from the Mouse Tissue Factor Pathway Inhibitor (TFPI) Gene
Jen-Yea Chang
,
D. Monroe
,
J. Oliver
,
H. Roberts
Thrombosis and Haemostasis
1999
Corpus ID: 46032566
Summary Tissue factor pathway inhibitor (TFPI) contains three Kunitz domains separated by two connecting regions. We have cloned…
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Highly Cited
1995
Highly Cited
1995
An anti-tissue factor pathway inhibitor (TFPI) monoclonal antibody recognized the third Kunitz domain (K3) of free-form TFPI but not lipoprotein-associated forms in plasma.
T. Abumiya
,
K. Enjyoji
,
Toshinori Kokawa
,
Y. Kamikubo
,
H. Kato
Journal of Biochemistry (Tokyo)
1995
Corpus ID: 21384212
Tissue factor pathway inhibitor (TFPI) is a Kunitz-type protease inhibitor with three tandem inhibitory domains, which inhibits…
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Highly Cited
1993
Highly Cited
1993
The functional expression of tissue factor by fibroblasts and endothelial cells under flow conditions.
E. Grabowski
,
Dina B. Zuckerman
,
Y. Nemerson
Blood
1993
Corpus ID: 25606663
The expression of tissue factor (TF) by a variety of vascular cell types under physiologic flow conditions is critical to factor…
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Highly Cited
1993
Highly Cited
1993
Evidence that the C-terminus of tissue factor pathway inhibitor (TFPI) is essential for its in vitro and in vivo interaction with lipoproteins.
S. Valentin
,
O. Nordfang
,
C. Bregengård
,
P. Wildgoose
Blood Coagulation and Fibrinolysis
1993
Corpus ID: 20028075
We have previously shown that the C-terminus of TFPI is essential for its anticoagulant activity. In the present study we have…
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Highly Cited
1990
Highly Cited
1990
Recombinant human extrinsic pathway inhibitor. Production, isolation, and characterization of its inhibitory activity on tissue factor-initiated coagulation reactions.
A. Pedersen
,
O. Nordfang
,
+7 authors
U. Hedner
Journal of Biological Chemistry
1990
Corpus ID: 23097945
Highly Cited
1989
Highly Cited
1989
Human plasma extrinsic pathway inhibitor activity: I. Standardization of assay and evaluation of physiologic variables.
T. Warr
,
B. Warn-Cramer
,
L. Rao
,
S. Rapaport
Blood
1989
Corpus ID: 30813930
An assay was standardized to measure extrinsic pathway inhibitor (EPI) activity in human plasma. Variables that could potentially…
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Highly Cited
1989
Highly Cited
1989
Factor VII and extrinsic pathway inhibitor in acute coronary disease
P. Sandset
,
P. Sirnes
,
U. Abildgaard
British Journal of Haematology
1989
Corpus ID: 24595833
Summary. This report describes studies on the activation of coagulation factor VII (FVII) and the inhibition of the extrinsic…
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Highly Cited
1989
Highly Cited
1989
Extrinsic pathway inhibitor in postoperative/posttraumatic septicemia: increased levels in fatal cases.
P. Sandset
,
O. Røise
,
A. Aasen
,
U. Abildgaard
Haemostasis
1989
Corpus ID: 46749928
The activity of the extrinsic pathway inhibitor (EPI), which is the factor-Xa-dependent inhibitor of the factor VIIa-tissue…
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1989
1989
Human plasma extrinsic pathway inhibitor activity: II. Plasma levels in disseminated intravascular coagulation and hepatocellular disease.
Ta Warr
,
L. Rao
,
S. Rapaport
Blood
1989
Corpus ID: 10546511
Plasma or serum extrinsic pathway inhibitor (EPI) activity was measured in 24 patients with disseminated intravascular…
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