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Tissue factor pathway inhibitor

Known as: TFPI, tissue factor pathway inhibitor (TFPI) 
National Institutes of Health

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TFPI geneTFPI wt Allele

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Tissue Factor Pathway Inhibitor, human

Papers overview

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Review
2016
Review
2016
Tissue Factor Pathway Inhibitor: Multiple Anticoagulant Activities for a Single Protein.
  • A. Mast
  • Arteriosclerosis, thrombosis, and vascular…
  • 2016
  • Corpus ID: 6675438
Tissue factor (TF) pathway inhibitor (TFPI) is an anticoagulant protein that inhibits early phases of the procoagulant response… 
Review
2014
Review
2014
Biology of tissue factor pathway inhibitor.
Recent studies of the anticoagulant activities of the tissue factor (TF) pathway inhibitor (TFPI) isoforms, TFPIα and TFPIβ, have… 
Review
2012
Review
2012
Tissue factor pathway inhibitor: structure-function.
TFPI is a multivalent, Kunitz-type proteinase inhibitor, which, due to alternative mRNA splicing, is transcribed in three… 
Highly Cited
2000
Highly Cited
2000
Expression, localization, and activity of tissue factor pathway inhibitor in normal and atherosclerotic human vessels.
Tissue factor (TF) pathway inhibitor (TFPI) is the major downregulator of the procoagulant activity of the TF-factor VIIa (FVIIa… 
Highly Cited
2000
Highly Cited
2000
Heparin induces synthesis and secretion of tissue factor pathway inhibitor from endothelial cells in vitro.
TFPI is a potent inhibitor of the extrinsic coagulation system constitutively synthesized by endothelial cells. A major portion… 
Highly Cited
1999
Highly Cited
1999
Cellular effects of heparin on the production and release of tissue factor pathway inhibitor in human endothelial cells in culture.
Tissue factor pathway inhibitor (TFPI), the major downregulator of procoagulant activity of the tissue factor-factor VIIa complex… 
Highly Cited
1998
Highly Cited
1998
Regulation of Extrinsic Pathway Factor Xa Formation by Tissue Factor Pathway Inhibitor*
Tissue factor (TF) pathway inhibitor (TFPI) regulates factor X activation through the sequential inhibition of factor Xa and the… 
Highly Cited
1998
Highly Cited
1998
Elevated TFPI in malignant disease: relation to cancer type and hypercoagulation
We have previously reported high levels of the coagulation inhibitor TFPI in the blood of patients with gastrointestinal cancer… 
Highly Cited
1998
Highly Cited
1998
Specific expression of PP5/TFPI2 mRNA by syncytiotrophoblasts in human placenta as revealed by in situ hybridization.
Highly Cited
1997
Highly Cited
1997
Increased tissue factor pathway inhibitor in patients with acute myocardial infarction
We examined hemostatic abnormalities in 23 patients with acute myocardial infarction (AMI), 10 with pulmonary embolism (PE), and… 
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