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Tissue Factor Pathway Inhibitor, human

Known as: Extrinsic Pathway Inhibitor, EPI, LACI 
Tissue factor pathway inhibitor (304 aa, ~35 kDa) is encoded by the human TFPI gene. This protein plays a role in the inhibition of blood coagulation… 
National Institutes of Health

Related topics

Related topics

7 relations
Extracellular SpaceGenes, RegulatorRegulation of ProteolysisTFPI gene

Broader (1)

Tissue factor pathway inhibitor

Papers overview

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Review
2015
Review
2015
Thrombomodulin/activated protein C system in septic disseminated intravascular coagulation
The thrombomodulin (TM)/activated protein C (APC) system plays an important role in maintaining the homeostasis of thrombosis and… 
Highly Cited
2012
Highly Cited
2012
Gene location and DNA density determine transcription factor distributions in Escherichia coli
The diffusion coefficient of the transcription factor LacI within living Escherichia coli has been measured directly by in vivo… 
Review
2009
Review
2009
Regulation of TFPI function by protein S
Summary.  Protein S is an anticoagulant cofactor of full‐length tissue factor pathway inhibitor (TFPI) that facilitates optimal… 
Review
2001
Review
2001
Structure and Biology of Tissue Factor Pathway Inhibitor
Summary Human tissue factor pathway inhibitor (TFPI) is a modular protein comprised of three Kunitz type domains flanked by… 
Highly Cited
2001
Highly Cited
2001
RelE, a global inhibitor of translation, is activated during nutritional stress
The stringent response is defined as the physiological changes elicited by amino acid starvation. Many of these changes depend on… 
Highly Cited
2000
Highly Cited
2000
SsrA‐mediated tagging and proteolysis of LacI and its role in the regulation of lac operon
SsrA RNA of Escherichia coli, also known as 10Sa RNA or tmRNA, acts both as tRNA and mRNA when ribosomes are paused at the 3′ end… 
Highly Cited
2000
Highly Cited
2000
Thromboresistance of balloon-injured porcine carotid arteries after local gene transfer of human tissue factor pathway inhibitor.
BACKGROUND Tissue factor pathway inhibitor (TFPI) is an endogenous inhibitor of factor Xa and the coagulant initiator complex… 
Highly Cited
1999
Highly Cited
1999
Cellular effects of heparin on the production and release of tissue factor pathway inhibitor in human endothelial cells in culture.
Tissue factor pathway inhibitor (TFPI), the major downregulator of procoagulant activity of the tissue factor-factor VIIa complex… 
Highly Cited
1998
Highly Cited
1998
Elevated TFPI in malignant disease: relation to cancer type and hypercoagulation
We have previously reported high levels of the coagulation inhibitor TFPI in the blood of patients with gastrointestinal cancer… 
Highly Cited
1997
Highly Cited
1997
von Willebrand Factor and Factor VIII: C in Acute Cerebrovascular Disease
Summary Background. Elevated von Willebrand factor (vWF) is a risk factor in the development of acute myocardial infarction. The… 
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