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TFF1 protein, human

Known as: breast cancer-estrogen induced protein, human, Gastrointestinal Trefoil Protein PS2, Trefoil Protein 1 
Trefoil factor 1 (84 aa, ~9 kDa) is encoded by the human TFF1 gene. This protein is involved in the maintenance of the gastrointestinal mucosa.
National Institutes of Health

Related topics

Related topics

22 relations
Breast CarcinomaCell Cycle ProgressionCell MaintenanceDuodenum

Broader (4)

Growth InhibitorsGrowth SubstancesNeoplasm ProteinsTrefoil Factor-1

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2004
Highly Cited
2004
Immunoassays of human trefoil factors 1 and 2: measured on serum from patients with inflammatory bowel disease
Background: The trefoil factors (TFF1–3) are cysteine‐rich peptides expressed in the gastrointestinal tract where they play a… 
2004
2004
Symmetry of dipositronium Ps2.
We work out the complete symmetry and spin problem for diatomic positronium Ps2 for the ground and singly excited states of zero… 
2002
2002
Neurotoxic mechanisms by Alzheimer's disease-linked N141I mutant presenilin 2.
Although it has been established that oxidative stress mediates cytotoxicity by familial Alzheimer's disease (FAD)-linked mutants… 
Highly Cited
1999
Highly Cited
1999
Hepatocyte nuclear factor 3 (winged helix domain) activates trefoil factor gene TFF1 through a binding motif adjacent to the TATAA box.
The winged helix transcription factors HNF-3/FKH (forkhead homologs) activate endodermal-derived and acute-phase gene expression… 
Highly Cited
1999
Highly Cited
1999
Trefoil factor-2, human spasmolytic polypeptide, promotes branching morphogenesis in MCF-7 cells.
Members of the trefoil factor (TFF) family are highly expressed in endodermal ulcerative wound healing and selectively in… 
1999
1999
Integrity and Activity of Photosystem 2 Complexes Isolated from the Thermophilic Cyanobacterium Synechococcus Elongatus Using Various Detergents
The efficiency in selective extraction of photosystem (PS) 2 oxygen evolving complexes was compared among seven detergents. These… 
Highly Cited
1998
Highly Cited
1998
Dimerization of human pS2 (TFF1) plays a key role in its protective/healing effects
Human pS2 (trefoil factor family 1, TFF1), a 60‐amino acid member of the trefoil peptide family, forms dimers via Cys58 and may… 
1995
1995
EFFECT OF CADMIUM STRESS ON GROWTH AND PHOTO- SYNTHESIS OF YOUNG BARLEY (H. vulgare L.) PLANTS. 2. STRUCTURAL AND FUNCTIONAL CHANGES IN THE PHOTOSYNTHETIC APPARATUS
Summary. The influence of Cd-stress on the structure and functional activity of the photosynthetic apparatus of 15-day-old barley… 
1995
1995
Synaptic transmission and paired-pulse behaviour of CA1 pyramidal cells in hippocampal slices from a hibernator at low temperature: importance of ionic environment
1991
1991
Uterine estrogen receptor-DNA complexes: effects of different ERE sequences, ligands, and receptor forms.
Previous studies used the gel retardation assay to examine the binding of the mouse estrogen receptor (ER) to the estrogen… 
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