TFF1 protein, human

Known as: breast cancer-estrogen induced protein, human, Gastrointestinal Trefoil Protein PS2, Trefoil Protein 1 
Trefoil factor 1 (84 aa, ~9 kDa) is encoded by the human TFF1 gene. This protein is involved in the maintenance of the gastrointestinal mucosa.
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2011
2011
Although trefoil factor 1 (TFF1; previously named pS2) is abnormally expressed in about 50% of human breast tumors, its… (More)
  • figure 1
  • figure 3
  • figure 4
  • figure 5
  • figure 6
Is this relevant?
Highly Cited
2011
Highly Cited
2011
BACKGROUND & AIMS Epigenetic alterations have been correlated with field cancerization in human patients, but evidence from… (More)
Is this relevant?
2011
2011
Trefoil factor 1 (TFF1) is a tumor suppressor gene that encodes a peptide belonging to the trefoil factor family of protease… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2005
Highly Cited
2005
Amyloid beta-peptide (Abeta), which plays a central role in Alzheimer's disease, is generated by presenilin-dependent gamma… (More)
Is this relevant?
2004
2004
Why Helicobacter pylori colonizes only gastric tissue is unknown. It is found on gastric mucus-secreting cells and in the… (More)
Is this relevant?
Highly Cited
2002
Highly Cited
2002
The human trefoil protein TFF1 is a small cysteine-rich secreted protein that is frequently expressed in breast tumors under the… (More)
Is this relevant?
Highly Cited
2000
Highly Cited
2000
Endoproteolysis of β-amyloid precursor protein (βAPP) and Notch requires conserved aspartate residues in presenilins 1 and 2 (PS1… (More)
  • figure 1
  • figure 2
  • figure 3
Is this relevant?
2000
2000
BACKGROUND TFF1 is a 6.5 kDa secreted protein that is expressed predominantly in normal gastric mucosa. It is coexpressed with… (More)
  • figure 1
  • figure 2
  • table 1
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
1998
Highly Cited
1998
Mutations in two related genes, presenilin 1 and 2 presenilin 2 (PS1 and PS2), cosegregate with Alzheimer's disease. PS1 and PS2… (More)
Is this relevant?
Highly Cited
1978
Highly Cited
1978
1. A study has been made of the tension responses and sarcomere length changes produced by servo-controlled stretches applied to… (More)
Is this relevant?