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TCL1A wt Allele

Known as: Oncogene TCL1, T-Cell Leukemia/Lymphoma 1A wt Allele, TCL1 
Human TCL1A wild-type allele is located in the vicinity of 14q32.1 and is approximately 4 kb in length. This allele, which encodes T-cell leukemia… 
National Institutes of Health

Related topics

Related topics

6 relations
14q32.1Leukemia, T-Cell, ChronicProtein phosphorylationSignal Transduction

Narrower (1)

T-Cell Leukemia/Lymphoma Protein 1A

Broader (1)

TCL1A gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2012
2012
Stromal cells modulate TCL1 expression, interacting AP-1 components and TCL1-targeting micro-RNAs in chronic lymphocytic leukemia
The tissue microenvironment in chronic lymphocytic leukemia (CLL) has an increasingly recognized role in disease progression, but… 
Highly Cited
2009
Highly Cited
2009
T Cell Leukemia/Lymphoma 1 and Galectin-1 Regulate Survival/Cell Death Pathways in Human Naive and IgM+ Memory B Cells through Altering Balances in Bcl-2 Family Proteins1
BCR signaling plays a critical role in purging the self-reactive repertoire, or in rendering it anergic to establish self… 
2007
2007
The TCL1 oncoprotein binds the RNase PH domains of the PNPase exoribonuclease without affecting its RNA degrading activity.
2006
2006
Meta-Analysis of Differentiating Mouse Embryonic Stem Cell Gene Expression Kinetics Reveals Early Change of a Small Gene Set
Stem cell differentiation involves critical changes in gene expression. Identification of these should provide endpoints useful… 
2003
2003
Two‐dimensional molecular profiling of mantle cell lymphoma
The present research establishes standard two‐dimensional (2‐D) maps for control, reactive lymph node and non‐Hodgkin's lymphoma… 
2003
2003
Sp1 Transactivation of the TCL1 Oncogene*
Cis-regions and trans-factors controllingTCL1 oncogene expression are not known. We identified the functional TCL1 promoter by… 
2003
2003
TNFα-Induced Apoptosis and Integrin Switching in Human Extravillous Trophoblast Cell Line1
Abstract Differentiation of extravillous trophoblast cells (EVT) to an invasive phenotype plays an essential role in establishing… 
Review
2003
Review
2003
TCL1: a new drug target in lymphoid and germ-cell malignancies?
1999
1999
Chromosomal imbalances in adult T-cell leukemia revealed by comparative genomic hybridization: gains at 14q32 and 2p16-22 in cell lines
AbstractComparative genomic hybridization was used to identify chromosomal imbalances in eight cell lines and 12 blood samples… 
1997
1997
Crystal structure of p14TCL1, an oncogene product involved in T-cell prolymphocytic leukemia, reveals a novel beta-barrel topology.
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