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TCL1A gene

Known as: TCL1, LYMPHOMA/LEUKEMIA, T-CELL, T-CELL LEUKEMIA/LYMPHOMA 1A 
This gene is involved in signal transduction.
National Institutes of Health

Related topics

Related topics

6 relations
Leukemia, T-Cell, ChronicProtein phosphorylationSignal TransductionT-Cell Leukemia/Lymphoma Protein 1A

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TCL1A wt Allele

Papers overview

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2014
2014
AKT-pathway inhibition in chronic lymphocytic leukemia reveals response relationships defined by TCL1.
Cell survival in chronic lymphocytic leukemia (CLL) largely depends on B-cell receptor-induced AKT activation. Gain-of-function… 
2014
2014
Genotype, allele and haplotype frequencies of four TCL1A gene polymorphisms associated with musculoskeletal toxicity in the South Indian descent
Introduction: Decline in circulating estrogen levels causes lessening of bone mass accompanied with musculoskeletal pain, which… 
2007
2007
The TCL1 oncoprotein binds the RNase PH domains of the PNPase exoribonuclease without affecting its RNA degrading activity.
Highly Cited
2005
Highly Cited
2005
Patterned CpG methylation of silenced B cell gene promoters in classical Hodgkin lymphoma-derived and primary effusion lymphoma cell lines.
2003
2003
Sp1 Transactivation of the TCL1 Oncogene*
Cis-regions and trans-factors controllingTCL1 oncogene expression are not known. We identified the functional TCL1 promoter by… 
2001
2001
Telomeric associations and chromosome instability in ataxia telangiectasia T cells characterized by TCL1 expression.
2000
2000
Backbone dynamics and solution structure refinement of the 15N-labeled human oncogenic protein p13MTCP1: Comparison with X-ray data
Two related oncogenes, TCL1 and MTCP1, are overexpressed in certain T-cell prolymphocytic leukemias as a result of chromosomal… 
2000
2000
Purification and characterization of recombinant forms of murine Tcl1 proteins.
The TCL1 gene, which is located on chromosome 14, plays a major role in human hematopoietic malignancies and encodes a 14-kDa… 
1998
1998
Amplification of the TCL1 flanking region at 14q32.1 with no TCL1 gene transcription in a patient with peripheral T cell lymphoma
Cytogenetic and molecular-genetic characteristics in peripheral T cell lymphoma (PTL) have not been well defined, except for… 
1997
1997
Crystal structure of p14TCL1, an oncogene product involved in T-cell prolymphocytic leukemia, reveals a novel beta-barrel topology.
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