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T-Cell Leukemia/Lymphoma Protein 1A

Known as: p14 TCL1, TCL1A, Oncogene TCL1 
T-cell leukemia/lymphoma protein 1A (114 aa, ~13 kDa) is encoded by the human TCL1A gene. This protein is involved in signal transduction activation… 
National Institutes of Health

Related topics

Related topics

7 relations
Homo sapiensLeukemia, T-Cell, ChronicProtein phosphorylationSignal Transduction

Broader (1)

TCL1A wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2017
Review
2017
Immune Mediator Pharmacogenomics: TCL1A SNPs and Estrogen-Dependent Regulation of Inflammation.
This review describes the important functional implications of TCL1A single nucleotide polymorphisms (SNPs) discovered during… 
2016
2016
TCL1 expression patterns in Waldenström macroglobulinemia
The oncogenic role of TCL1 in chronic lymphocytic leukemia is well established in transgenic mice. TCL1 expression in other B… 
2015
2015
Overexpression of salivary-type amylase reduces the sensitivity to bortezomib in multiple myeloma cells
Amylase-producing myeloma exhibits refractoriness to chemotherapy and a dismal prognosis. In this study, we established a human… 
Review
2014
Review
2014
Take (STAT)5: jazzing up T-cell leukemia.
Although significant strides are being made in the molecular classification of mature T-cell lymphomas and leukemias (MTCLL),2… 
2014
2014
Genotype, allele and haplotype frequencies of four TCL1A gene polymorphisms associated with musculoskeletal toxicity in the South Indian descent
Introduction: Decline in circulating estrogen levels causes lessening of bone mass accompanied with musculoskeletal pain, which… 
2011
2011
P1-06-02: Correlation between Gene Variants in CYP19 (Aromatase) and TCL1A with Disease and Tolerability Endpoints in the ATAC Trial.
Aim: To assess whether candidate polymorphisms in CYP19 (aromatase) and TCL1A were associated with recurrence, musculoskeletal… 
2010
2010
New pharmacogenomic paradigm in breast cancer treatment.
The impact of genetics and genomics on clinical oncology has been profound. Panels that detect the expression of oncogenes (eg… 
2010
2010
Pharmacologic interception in T-cell leukemia 1A associated pathways as a treatment rationale for chronic lymphocytic leukemia
Recent therapeutic advances in chronic lymphocytic leukemia (CLL) are reflected by high response rates in most subsets of… 
2009
2009
miR-34b/miR-34c: a regulator of TCL1 expression in 11q− chronic lymphocytic leukaemia?
2005
2005
Identification of TCL1A as an immunohistochemical marker of adverse outcome in diffuse large B-cell lymphomas.
We used a combination of DNA-microarray and tissue-microarray (TMA) analyses to identify markers that could be routinely used to… 
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