• Publications
  • Influence
European Renal Best Practice Guideline on kidney donor and recipient evaluation and perioperative care.
The European Best Practice Guideline group (EBPG) issued guidelines on the evaluation and selection of kidney donor and kidney transplant candidates, as well as post-transplant recipient care, in theExpand
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Rabbit antithymocyte globulin-induced serum sickness disease and human kidney graft survival.
BACKGROUND Rabbit-generated antithymocyte globulins (ATGs), which target human T cells, are widely used as immunosuppressive agents during treatment of kidney allograft recipients. However, ATGs canExpand
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Identification of renal Cd36 as a determinant of blood pressure and risk for hypertension
To identify renally expressed genes that influence risk for hypertension, we integrated expression quantitative trait locus (QTL) analysis of the kidney with genome-wide correlation analysis of renalExpand
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Haplotypic Structure of ABCB1/MDR1 Gene Modifies the Risk of the Acute Allograft Rejection in Renal Transplant Recipients
Background. Bioavailability of tacrolimus (Tac) and cyclosporine is determined by cytochrome P450IIIA and by P-glycoprotein encoded by the CYP3A4/CYP3A5 and ABCB1 genes. Polymorphisms in these genesExpand
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Strategies to increase the donor pool and access to kidney transplantation: an international perspective
In this position article, DESCARTES (Developing Education Science and Care for Renal Transplantation in European States) board members describe the current strategies aimed at expanding living andExpand
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Long-term outcomes of pre-emptive valganciclovir compared with valacyclovir prophylaxis for prevention of cytomegalovirus in renal transplantation.
Prevention of cytomegalovirus (CMV) is essential in organ transplantation. The two main strategies are pre-emptive therapy, in which one screens for and treats asymptomatic CMV viremia, and universalExpand
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Polymorphism of interleukin-18 promoter influences the onset of kidney graft function after transplantation.
It has been well recognized that the promoter polymorphisms of interleukin-18 (IL-18) influence the level of cytokine expression. In our previously published data, we showed constitutive IL-18Expand
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Genetic Variability of Major Inflammatory Mediators Has No Impact on the Outcome of Kidney Transplantation
Background. Functionally relevant polymorphisms in genes of the Th1 and Th2-inflammatory pathway influence the susceptibility to acute rejection (AR), chronic allograft nephropathy (CAN), andExpand
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The FTO gene polymorphism is associated with end-stage renal disease: two large independent case-control studies in a general population.
BACKGROUND Genome-wide association studies identified the FTO (fat mass and obesity gene) gene as an important determinant of body weight. More recently, the FTO gene was reported to be associatedExpand
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Heightened Expression of the Cytotoxicity Receptor NKG2D Correlates with Acute and Chronic Nephropathy After Kidney Transplantation
The activating cytotoxicity receptor NKG2D binds to stress‐regulated molecules encoded by the major histocompatibility complex class I chain‐related (MIC) and UL‐16‐binding protein (ULBP)/retinoicExpand
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