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TAT 59

Known as: Phenol, 4-(1-(4-(2-(dimethylamino)ethoxy)phenyl)-2-(4-(1-methylethyl)phenyl)-1-butenyl)-, dihydrogen phosphate (ester), (E)-, TAT-59 
National Institutes of Health

Papers overview

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Review
2004
Review
2004
  • V. Jordan
  • Breast Cancer Research and Treatment
  • 2004
  • Corpus ID: 5879637
SummaryIn 1973, McGuire and Chamness (In: O'Malley BW and Means AR (eds) Receptors for Reproductive Hormones, Plenum Press… Expand
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Highly Cited
2004
Highly Cited
2004
AbstractPurpose. To evaluate the potential of phosphate ester prodrugs to significantly improve the absorptive flux of poorly… Expand
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2003
2003
Many oral phosphate prodrugs have failed to improve the rate or extent of absorption compared to their insoluble parent drugs… Expand
2000
2000
Purpose: We evaluated miproxifene phosphate (TAT-59) to elucidate its efficacy in antiestrogen therapy for breast cancer patients… Expand
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1998
1998
Phase I study of TAT-59 (Miproxifen), an antiestrogen developed in Japan for breast cancer, was conducted with the collaboration… Expand
1997
1997
Abstract Purpose: The purpose of this study was to clarify the mechanism(s) of antiestrogenic action of DP-TAT-59 ((Z)-2-(4-(1-(4… Expand
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1993
1993
(E)-4-[1-[4-[2-(Dimethylamino)ethoxy]phenyl]-2-(4-isopropyl) phenyl]-1-butenyl]phenyl monophosphate (TAT-59) is a new drug for… Expand
1992
1992
The antitumor activity of a newly synthesized triphenylethylene derivative {(E)‐4‐[1‐4‐[2‐(dimethylamino)ethoxy‐phenyl]‐2‐(4… Expand
1992
1992
DP-TAT-59, (Z)-2-(4-(1-(4-hydroxyphenyl)-2-(4-isopropylphenyl)-1-butenyl) phenoxy)-N, N-dimethylethylamine, has been reported to… Expand
1990
1990
The antiestrogenic action of TAT-59 [(E)-4-[1-[4-[2-(dimethylamino)ethoxy]-phenyl]-2-(4-isopropyl) phenyl-1-butenyl]phenyl… Expand