Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

TAT 59

Known as: Phenol, 4-(1-(4-(2-(dimethylamino)ethoxy)phenyl)-2-(4-(1-methylethyl)phenyl)-1-butenyl)-, dihydrogen phosphate (ester), (E)-, TAT-59 
 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2004
2004
TAT-59 suppressed the growth fo DMBA-induced mammary tumors in rats earlier and more strongly than tamoxifen (TAM). After oral… Expand
  • figure 1
  • table 1
  • table 2
  • table 3
  • figure 2
Is this relevant?
Highly Cited
2004
Highly Cited
2004
AbstractPurpose. To evaluate the potential of phosphate ester prodrugs to significantly improve the absorptive flux of poorly… Expand
  • figure 1
  • table I
  • figure 2
  • table II
  • table III
Is this relevant?
2003
2003
Many oral phosphate prodrugs have failed to improve the rate or extent of absorption compared to their insoluble parent drugs… Expand
Is this relevant?
2000
2000
Purpose: We evaluated miproxifene phosphate (TAT-59) to elucidate its efficacy in antiestrogen therapy for breast cancer patients… Expand
  • table 1
  • figure 1
  • figure 2
  • table 2
  • figure 3
Is this relevant?
1997
1997
Abstract Purpose: The purpose of this study was to clarify the mechanism(s) of antiestrogenic action of DP-TAT-59 ((Z)-2-(4-(1-(4… Expand
  • figure 1
  • figure 3
  • figure 5
  • figure 6
  • figure 7
Is this relevant?
1993
1993
(E)-4-[1-[4-[2-(Dimethylamino)ethoxy]phenyl]-2-(4-isopropyl) phenyl]-1-butenyl]phenyl monophosphate (TAT-59) is a new drug for… Expand
Is this relevant?
1993
1993
The growth inhibitory activity and influences on cell-cycle progression of tamoxifen (TAM) and its derivatives [toremifene(NK… Expand
Is this relevant?
1992
1992
The antitumor activity of a newly synthesized triphenylethylene derivative {(E)‐4‐[1‐4‐[2‐(dimethylamino)ethoxy‐phenyl]‐2‐(4… Expand
Is this relevant?
1992
1992
DP-TAT-59, (Z)-2-(4-(1-(4-hydroxyphenyl)-2-(4-isopropylphenyl)-1-butenyl) phenoxy)-N, N-dimethylethylamine, has been reported to… Expand
Is this relevant?
1990
1990
The antiestrogenic action of TAT-59 [(E)-4-[1-[4-[2-(dimethylamino)ethoxy]-phenyl]-2-(4-isopropyl) phenyl-1-butenyl]phenyl… Expand
Is this relevant?