T-cell receptor complex location

Known as: T-lymphocyte receptor complex location, T lymphocyte receptor complex, TCR complex location 
A protein complex that contains a disulfide-linked heterodimer of T cell receptor (TCR) chains, which are members of the immunoglobulin superfamily… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1984-2018
0204019842018

Papers overview

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Highly Cited
2004
Highly Cited
2004
MOTIVATION To create the enormous diversity of 10(12) immunoglobulins (IG) and T cell receptors (TR) per individual, very complex… (More)
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Highly Cited
2003
Highly Cited
2003
An important pathway for immune tolerance is provided by thymic-derived CD25+ CD4+ T cells that suppress other CD25- autoimmune… (More)
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Highly Cited
2001
Highly Cited
2001
T-cell activation requires clustering of a threshold number of T-cell receptors (TCRs) at the site of antigen presentation, a… (More)
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Highly Cited
1998
Highly Cited
1998
T-cell receptors (TCRs) upon binding to peptide-MHC ligands transduce signals in T lymphocytes. Tyrosine phosphorylations in the… (More)
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Highly Cited
1998
Highly Cited
1998
The efficacy of thalidomide (alpha-phthalimido-glutarimide) therapy in leprosy patients with erythema nodosum leprosum is thought… (More)
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Highly Cited
1996
Highly Cited
1996
NF-ATp is a member of a family of genes that encodes the cytoplasmic component of the nuclear factor of activated T cells (NF-AT… (More)
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Highly Cited
1996
Highly Cited
1996
The CD45 transmembrane glycoprotein has been shown to be a protein phosphotyrosine phosphatase and to be important in signal… (More)
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Highly Cited
1995
Highly Cited
1995
Like other cell-surface receptors with intrinsic or associated protein-tyrosine kinase activity, the T-cell receptor complex… (More)
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Highly Cited
1995
Highly Cited
1995
The Syk cytoplasmic protein-tyrosine kinase has two amino-terminal SH2 domains and a carboxy-terminal catalytic domain. Syk, and… (More)
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Highly Cited
1992
Highly Cited
1992
Immature T cells and some T cell hybridomas undergo apoptotic cell death when activated through the T cell receptor complex, a… (More)
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