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T-Cell Leukemia/Lymphoma Protein 1A

Known as: p14 TCL1, TCL1A, Oncogene TCL1 
T-cell leukemia/lymphoma protein 1A (114 aa, ~13 kDa) is encoded by the human TCL1A gene. This protein is involved in signal transduction activation… 
National Institutes of Health

Related topics

Related topics

7 relations
Homo sapiensLeukemia, T-Cell, ChronicProtein phosphorylationSignal Transduction

Broader (1)

TCL1A wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2016
Highly Cited
2016
High-level ROR1 associates with accelerated disease progression in chronic lymphocytic leukemia.
ROR1 is an oncoembryonic orphan receptor found on chronic lymphocytic leukemia (CLL) B cells, but not on normal postpartum… 
2016
2016
The composition of surface wax on trichomes of Arabidopsis thaliana differs from wax on other epidermal cells.
To protect plants against biotic and abiotic stress, the waxy cuticle must coat all epidermis cells. Here, two independent… 
Highly Cited
2013
Highly Cited
2013
B-Cell-Related Biomarkers of Tolerance are Up-Regulated in Rejection-Free Kidney Transplant Recipients
Background Molecular signatures have recently been identified in operationally tolerant long-term kidney transplant patients… 
Highly Cited
2011
Highly Cited
2011
MicroRNA profiles of t(14;18)-negative follicular lymphoma support a late germinal center B-cell phenotype.
A total of 90% of follicular lymphomas (FLs) harbor the translocation t(14;18) leading to deregulated BCL2 expression. Conversely… 
2011
2011
LPL is the strongest prognostic factor in a comparative analysis of RNA-based markers in early chronic lymphocytic leukemia
Background The expression levels of LPL, ZAP70, TCL1A, CLLU1 and MCL1 have recently been proposed as prognostic factors in… 
Highly Cited
2008
Highly Cited
2008
Pathway analysis of primary central nervous system lymphoma.
Primary central nervous system (CNS) lymphoma (PCNSL) is a diffuse large B-cell lymphoma (DLBCL) confined to the CNS. A genome… 
Review
2007
Review
2007
Murine models of chronic lymphocytic leukaemia: role of microRNA‐16 in the New Zealand Black mouse model
Mouse models are valuable tools in the study of human chronic lymphocytic leukaemia (CLL). The New Zealand Black (NZB) strain is… 
Highly Cited
2006
Highly Cited
2006
Effect of rapamycin on mouse chronic lymphocytic leukemia and the development of nonhematopoietic malignancies in Emu-TCL1 transgenic mice.
Chronic lymphocytic leukemia (CLL) is the most common leukemia in the world. The TCL1 gene, responsible for prolymphocytic T cell… 
Highly Cited
2002
Highly Cited
2002
Dysregulated TCL1 promotes multiple classes of mature B cell lymphoma
The TCL1 protooncogene is overexpressed in many mature B cell lymphomas, especially from AIDS patients. To determine whether… 
Highly Cited
2002
Highly Cited
2002
Identification of Akt Association and Oligomerization Domains of the Akt Kinase Coactivator TCL1
ABSTRACT Serine/threonine kinase Akt/protein kinase B, the cellular homologue of the transforming viral oncogene v-Akt, plays a… 
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