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T 30177

Known as: T30177, T-30177, AR 177 
 
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
T30177 is a G-rich oligonucleotide with the sequence (GTGGTGGGTGGGTGGGT) which inhibits the HIV-1 integrase activity at nanomolar… Expand
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Highly Cited
2010
Highly Cited
2010
Resistance to raltegravir (RAL), the first HIV-1 integrase (IN) inhibitor approved by the FDA, involves three genetic pathways… Expand
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2004
2004
Zintevir is an oligonucleotide analogue, which has the phosphorothioate modification at both termini, that forms a K(+)-induced… Expand
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Review
2001
Review
2001
Virtually all the compounds that are currently used, or under advanced clinical trial, for the treatment of HIV infections… Expand
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Highly Cited
1998
Highly Cited
1998
Recently, we have described the design and characterization of oligonucleotides containing only G and T bases,i.e. T30695 and… Expand
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Highly Cited
1997
Highly Cited
1997
Previously, we have described inhibition of HIV-1 infection by T30177, 5'-(GTGGTGGGTGGGTGGGT)-3', an oligonucleotide that is a… Expand
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1997
1997
Oligonucleotides that can form a highly stable intramolecular four-stranded DNA structure containing two stacked guanosine… Expand
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Highly Cited
1996
Highly Cited
1996
We have identified a potentially therapeutic anti-human immunodeficiency virus (HIV)-1 oligonucleotide composed entirely of… Expand
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Highly Cited
1996
Highly Cited
1996
An oligonucleotide (T30177) composed entirely of deoxyguanosine and thymidine has previously been shown to fold upon itself in… Expand
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1995
1995
T30177, an oligonucleotide composed of only deoxyguanosine and thymidine, is 17 nucleotides in length and contains single… Expand
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