Succinate-semialdehyde dehydrogenase

Known as: NAD(+)-Dependent Succinic Semialdehyde Dehydrogenase, Dehydrogenase, Succinic Semialdehyde, Dehydrogenase, Succinate Semialdehyde 
An enzyme that plays a role in the GLUTAMATE and butanoate metabolism pathways by catalyzing the oxidation of succinate semialdehyde to SUCCINATE… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1954-2017
010203019542016

Papers overview

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Highly Cited
2006
Highly Cited
2006
We show here that children with pyridoxine-dependent seizures (PDS) have mutations in the ALDH7A1 gene, which encodes antiquitin… (More)
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2004
2004
Succinate-semialdehyde dehydrogenase (SSADH) deficiency is a rare cause of learning disability. We have investigated SSADH to… (More)
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2004
2004
Mice with targeted deletion of the GABA catabolic enzyme succinic semialdehyde dehydrogenase (SSADH) manifest lethal tonic-clonic… (More)
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2004
2004
Murine succinate semialdehyde dehydrogenase (SSADH) deficiency (OMIM 271980; EC 1.2.1.24), a model of the corresponding human… (More)
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Highly Cited
2003
Highly Cited
2003
The gamma-aminobutyrate (GABA) shunt is a metabolic pathway that bypasses two steps of the tricarboxylic acid cycle, and it is… (More)
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2002
2002
Metabolite profiling in succinate semialdehyde dehydrogenase (SSADH; Aldh5a1-/-) deficient mice previously revealed elevated… (More)
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2002
2002
Therapeutic intervention for human succinic semialdehyde dehydrogenase (SSADH) deficiency (gamma-hydroxybutyric aciduria) has… (More)
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2001
2001
Succinate semialdehyde dehydrogenase (ALDH5A1, encoding SSADH deficiency is a defect of 4-aminobutyric acid (GABA) degradation… (More)
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Highly Cited
2000
Highly Cited
2000
Unknown compounds in polar fractions of Arabidopsis thaliana crude leaf extracts were identified on the basis of calculations of… (More)
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Highly Cited
1999
Highly Cited
1999
Gamma-aminobutyric acid (GABA), a four-carbon non-protein amino acid, is a significant component of the free amino acid pool in… (More)
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