I. McGregor

Publications283
h-index63
Citations12,743
Highly Influential Citations753
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The effects of predator odors in mammalian prey species: A review of field and laboratory studies
Prey species show specific adaptations that allow recognition, avoidance and defense against predators. For many mammalian species this includes sensitivity towards predator-derived odors. The… Expand
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‘When a rat smells a cat’: the distribution of Fos immunoreactivity in rat brain following exposure to a predatory odor
Wistar rats were exposed to a fabric collar that had been worn by a domestic cat. Exposure took place in an open rectangular arena containing a small wooden "hide box". Rats exposed to cat odor spent… Expand
  • 438
  • 28
Adolescent Rats Find Repeated Δ9-THC Less Aversive Than Adult Rats but Display Greater Residual Cognitive Deficits and Changes in Hippocampal Protein Expression Following Exposure
The current study examined whether adolescent rats are more vulnerable than adult rats to the lasting adverse effects of cannabinoid exposure on brain and behavior. Male Wistar rats were repeatedly… Expand
  • 243
  • 22
  • Open Access
Defensive behavior in rats towards predatory odors: a review
Studies of the response of rodents to predatory odors (mainly cat) have provided useful insights into the nature of defensive behavior. This article reviews work in this area with a focus on a… Expand
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Not all ‘predator odours’ are equal: cat odour but not 2,4,5 trimethylthiazoline (TMT; fox odour) elicits specific defensive behaviours in rats
The behavioural responses to two commonly used 'predator odours' were assessed in male Wistar rats. Cat odour was presented to rats in the form of a piece of collar that had been worn by a domestic… Expand
  • 208
  • 19
Aversive effects of the synthetic cannabinoid CP 55,940 in rats
A series of experiments investigated the behavioral and hedonic effects of the synthetic cannabinoid CP 55,940 in male Wistar rats. CP 55,940 had a biphasic effect on locomotor activity, with a 10… Expand
  • 167
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Increased motivation for beer in rats following administration of a cannabinoid CB1 receptor agonist.
A series of experiments examined the effects of the cannabinoid CB1 receptor agonist CP 55,940 ((-)-cis-3-[2-hydroxy-4-(1,1-dimethylheptyl)phenyl]-trans-4-(3-hyd roxypropyl)cyclohexanol) on the… Expand
  • 237
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Chronic cannabinoid exposure produces lasting memory impairment and increased anxiety in adolescent but not adult rats
Although many studies have examined the acute behavioural effects of cannabinoids in rodents, few have examined the lasting effects of cannabinoids at different developmental ages. This study… Expand
  • 260
  • 17
  • Open Access
A role for oxytocin and 5-HT1A receptors in the prosocial effects of 3,4 methylenedioxymethamphetamine (“ecstasy”)
The drug 3,4 methylenedioxymethamphetamine (MDMA; ecstasy) has a widely documented ability to increase feelings of love and closeness toward others. The present study investigated whether oxytocin, a… Expand
  • 192
  • 15
  • Open Access
Increased Anxiety 3 Months after Brief Exposure to MDMA (‘Ecstasy’) in Rats: Association with Altered 5-HT Transporter and Receptor Density
Male Wistar rats were treated with 3,4-methylenedioxymethamphetamine (MDMA, ‘Ecstasy’) using either a high dose (4 × 5 mg/kg over 4 h) or low dose (1 × 5 mg/kg over 4 h) regimen on each of 2… Expand
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