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ALDH5A1 gene

Known as: ALDEHYDE DEHYDROGENASE 5 FAMILY, MEMBER A1, aldehyde dehydrogenase 5 family member A1, SSDH 
National Institutes of Health

Related topics

Related topics

1 relation
Succinate-semialdehyde dehydrogenase

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Toxicologic/transport properties of NCS-382, a γ-hydroxybutyrate (GHB) receptor ligand, in neuronal and epithelial cells: Therapeutic implications for SSADH deficiency, a GABA metabolic disorder.
2016
2016
Phenotypic and chemotypic studies using Arabidopsis and yeast reveal that GHB converts to SSA and induce toxicity
γ-Hydroxybutyric acid (GHB) is a naturally occurring compound. It is detected in organisms such as yeasts, plants and mammals… 
2016
2016
A pharmacokinetic evaluation and metabolite identification of the GHB receptor antagonist NCS‐382 in mouse informs novel therapeutic strategies for the treatment of GHB intoxication
Gamma‐aminobutyric acid (GABA) is an endogenous inhibitory neurotransmitter and precursor of gamma‐hydroxybutyric acid (GHB). NCS… 
2008
2008
Saturation transfer difference NMR studies on substrates and inhibitors of succinic semialdehyde dehydrogenases.
2005
2005
Evidence for co-operativity in coenzyme binding to tetrameric Sulfolobus solfataricus alcohol dehydrogenase and its structural basis: fluorescence, kinetic and structural studies of the wild-type…
The interaction of coenzyme with thermostable homotetrameric NAD(H)-dependent alcohol dehydrogenase from the thermoacidophilic… 
2000
2000
Plant succinic semialdehyde dehydrogenase: dissection of nucleotide binding by surface plasmon resonance and fluorescence spectroscopy.
Recent kinetic studies revealed distinct modes of inhibition of mitochondrial Arabidopsis thaliana succinic semialdehyde… 
Highly Cited
1998
Highly Cited
1998
Is the single-state dominance realized in double-β-decay transitions?
In the single-state-dominance hypothesis ~SSDH! the decay rate of the two-neutrino double-b decay to the final ground state is… 
1989
1989
Succinic semialdehyde dehydrogenase deficiency associated with combined 4-hydroxybutyric and dicarboxylic acidurias: potential for clinical misdiagnosis based on urinary organic acid profiling.
Review
1979
Review
1979
GABA transaminase inhibitors.
In summary, several branched-chain fatty acids appeared to be competitive inhibitors of GABA-T and non-competitive inhibitors of… 
1976
1976
In vitro studies into the effect of inhibition of rat brain succinic semialdehyde dehydrogenase on GABA synthesis and degradation
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