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Subtilisin

Known as: Subtilisin [Chemical/Ingredient] 
A serine endopeptidase isolated from Bacillus subtilis. It hydrolyzes proteins with broad specificity for peptide bonds, and a preference for a large… Expand
National Institutes of Health

Papers overview

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Review
2019
Review
2019
Summary Background After acute coronary syndrome, diabetes conveys an excess risk of ischaemic cardiovascular events. A reduction… Expand
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Highly Cited
2017
Highly Cited
2017
BACKGROUND Evolocumab is a monoclonal antibody that inhibits proprotein convertase subtilisin–kexin type 9 (PCSK9) and lowers low… Expand
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Highly Cited
2015
Highly Cited
2015
BACKGROUND Alirocumab, a monoclonal antibody that inhibits proprotein convertase subtilisin-kexin type 9 (PCSK9), has been shown… Expand
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Highly Cited
2009
Highly Cited
2009
Proprotein convertase subtilisin/kexin type 9 (PCSK9) regulates serum LDL cholesterol (LDL-C) by interacting with the LDL… Expand
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Highly Cited
2007
Highly Cited
2007
Proprotein convertase subtilisin/kexin type 9 (PCSK9) promotes degradation of hepatic low density lipoprotein receptors (LDLR… Expand
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Highly Cited
2006
Highly Cited
2006
BACKGROUND A low plasma level of low-density lipoprotein (LDL) cholesterol is associated with reduced risk of coronary heart… Expand
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Highly Cited
2004
Highly Cited
2004
Lipid homeostasis is transcriptionally regulated by three DNA-binding proteins, designated sterol regulatory element-binding… Expand
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Highly Cited
2003
Highly Cited
2003
Autosomal dominant hypercholesterolemia (ADH; OMIM144400), a risk factor for coronary heart disease, is characterized by an… Expand
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Highly Cited
2000
Highly Cited
2000
Stomata are specialized cellular structures in the epidermis of aerial plant organs that control gas exchange (H(2)O release and… Expand
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Highly Cited
1992
Highly Cited
1992
Many viruses have membrane glycoproteins that are activated at cleavage sites containing multiple arginine and lysine residues by… Expand
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