Structure of germinal center of lymph node

Known as: Germinal Centers, Secondary lymphoid tissue, centers germinal 
The activated center of a lymphoid follicle in secondary lymphoid tissue where B-LYMPHOCYTES are stimulated by antigens and helper T cells (T… (More)

Topic mentions per year

Topic mentions per year

1941-2018
020040019412017

Papers overview

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Highly Cited
2010
Highly Cited
2010
Follicular lymphoma (FL) and the GCB subtype of diffuse large B-cell lymphoma (DLBCL) derive from germinal center B cells… (More)
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Highly Cited
2010
Highly Cited
2010
The germinal center (GC) reaction produces high-affinity antibodies by random mutation and selective clonal expansion of B cells… (More)
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Highly Cited
2008
Highly Cited
2008
Interleukin 17 (IL-17) is a cytokine associated with inflammation, autoimmunity and defense against some bacteria. Here we show… (More)
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Highly Cited
2004
Highly Cited
2004
Germinal center (GC) dark and light zones segregate cells undergoing somatic hypermutation and antigen-driven selection… (More)
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Highly Cited
2004
Highly Cited
2004
Diffuse large B-cell lymphoma (DLBCL) can be divided into prognostically important subgroups with germinal center B-cell-like… (More)
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Highly Cited
2000
Highly Cited
2000
Induced overexpression of AID in CH12F3-2 B lymphoma cells augmented class switching from IgM to IgA without cytokine stimulation… (More)
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Highly Cited
1999
Highly Cited
1999
We have identified a novel gene referred to as activation-induced deaminase (AID) by subtraction of cDNAs derived from switch… (More)
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Highly Cited
1999
Highly Cited
1999
Despite having several characteristics of naïve B cells, chronic lymphocytic leukemia (CLL) cells have been shown in some cases… (More)
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Highly Cited
1995
Highly Cited
1995
Structural alterations of the 5' noncoding region of the BCL-6 gene have been found in 40% of diffuse large cell lymphoma (DLCL… (More)
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Highly Cited
1994
Highly Cited
1994
Apoptosis, or programmed cell death, is a general mechanism for removal of unwanted cells from the immune system. It is… (More)
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