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Structure of germinal center of lymph node

Known as: Germinal Centers, Secondary lymphoid tissue, centers germinal 
The activated center of a lymphoid follicle in secondary lymphoid tissue where B-LYMPHOCYTES are stimulated by antigens and helper T cells (T… Expand
National Institutes of Health

Papers overview

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Review
2016
Review
2016
PURPOSE OF REVIEW Tissue reservoirs of HIV may promote the persistent immunopathology responsible for non-AIDS morbidity and data… Expand
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Highly Cited
2011
Highly Cited
2011
Follicular helper (T FH ) cells provide crucial signals to germinal center B cells undergoing somatic hypermutation and selection… Expand
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Highly Cited
2010
Highly Cited
2010
The germinal center (GC) reaction produces high-affinity antibodies by random mutation and selective clonal expansion of B cells… Expand
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Highly Cited
2007
Highly Cited
2007
MicroRNAs are small RNA species involved in biological control at multiple levels. Using genetic deletion and transgenic… Expand
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Highly Cited
2004
Highly Cited
2004
Diffuse large B-cell lymphoma (DLBCL) can be divided into prognostically important subgroups with germinal center B-cell-like… Expand
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Highly Cited
2004
Highly Cited
2004
Multiple sclerosis (MS) is characterized by synthesis of oligoclonal immunoglobulins and the presence of B-cell clonal expansions… Expand
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Highly Cited
2000
Highly Cited
2000
Induced overexpression of AID in CH12F3-2 B lymphoma cells augmented class switching from IgM to IgA without cytokine stimulation… Expand
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Highly Cited
1997
Highly Cited
1997
The gene encoding the BCL-6 transcriptional repressor is frequently translocated and mutated in diffuse large cell lymphoma. Mice… Expand
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Highly Cited
1996
Highly Cited
1996
To investigate the role of TNF alpha in the development of in vivo immune response we have generated TNF alpha-deficient mice by… Expand
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Review
1994
Review
1994
Germinal centers develop in the B cell follicles of secondary lymphoid tissues during T cell-dependent (TD) antibody responses… Expand
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