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Consensus proposals for a unified system of nomenclature of hepatitis C virus genotypes
These proposals provide the framework by which the HCV databases store and provide access to data on HCV, which will internationally coordinate the assignment of new genotypes and subtypes in the future. Expand
Taxonomy of the caliciviruses.
The International Committee on Taxonomy of Viruses (ICTV) has recently approved several proposals submitted by the present Caliciviridae Study Group. These proposals include the division of the… Expand
Processing of the envelope glycoproteins of pestiviruses
Using pulse-chase experiments, it is shown that a pestiviral glycoprotein precursor, E012, is formed that is processed into E0, E1, and E2 in an ordered fashion, and comparison of the sequences around the cleavage sites of pestiviruses suggests a general processing scheme for the structural glycoproteins. Expand
Molecular characterization of pestiviruses.
One remarkable property of pestiviruses is the existence of two biotypes that were recognized according to morphological changes they cause during growth in tissue culture cells, which arise by nonhomologous RNA recombination. Expand
Identification of Sympathetic Premotor Neurons in Medullary Raphe Regions Mediating Fever and Other Thermoregulatory Functions
- Kazuhiro Nakamura, K. Matsumura, +9 authors T. Kaneko
- Biology, Medicine
- The Journal of Neuroscience
- 9 June 2004
The present results suggest that VGLUT3-expressing neurons in the medullary raphe regions constitute excitatory neurons that could be categorized as a novel group of sympathetic premotor neurons for thermoregulatory functions, including fever. Expand
Genetic map of the calicivirus rabbit hemorrhagic disease virus as deduced from in vitro translation studies
The studies show that the N-terminal half of the ORF1 polyprotein is proteolytically cleaved to yield three nonstructural proteins of 16, 23, and 37 kDa (p16, p23, and p37, respectively). Expand
Rabbit hemorrhagic disease virus--molecular cloning and nucleotide sequencing of a calicivirus genome.
The RNA genome of rabbit hemorrhagic disease virus (RHDV) was molecularly cloned. The 5' terminal sequence of the genomic RNA was determined after PCR amplification of a G-tailed first strand cDNA… Expand
Hog Cholera Virus: Molecular Composition of Virions from a Pestivirus
Virions from hog cholera virus (HCV), a member of the genus Pestivirus, were analyzed by using specific antibodies. The nucleocapsid protein was found to be a 14-kDa molecule (HCV p14). An equivalent… Expand
Genetic and antigenic characterization of novel pestivirus genotypes: implications for classification.
Taking into account the host origin, the lack of differences concerning the course of disease, and the results of the genetic and antigenic analyses, it is suggested that BDV-1, BDv-2, andBDV-3 should be considered as major genotypes within the species BDV. Expand
Temporal Modulation of an Autoprotease Is Crucial for Replication and Pathogenicity of an RNA Virus
The biotype-specific modulation of NS2-3 autoprocessing indicates a crucial role of the NS2 autoprotease in the pathogenicity of BVDV, implying an essential function for NS3 in pestiviral RNA replication which cannot be supplied by its NS2. Expand