Steroid 17-alpha-Hydroxylase

Known as: alpha 17 hydroxylase, Steroid 17 alpha Hydroxylase, CYP17 
A microsomal cytochrome P450 enzyme that catalyzes the 17-alpha-hydroxylation of progesterone or pregnenolone and subsequent cleavage of the residual… (More)
National Institutes of Health

Papers overview

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Review
2004
Review
2004
Stress promotes adaptation, but prolonged stress leads over time to wear-and-tear on the body (allostatic load). Neural changes… (More)
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Review
2003
Review
2003
The brain controls both the physiologic and the behavioral coping responses to daily events as well as major stressors, and the… (More)
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Highly Cited
1999
Highly Cited
1999
Prostate cancer is the most common malignancy in males and is the second most common cause of cancer mortality in American men… (More)
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Highly Cited
1995
Highly Cited
1995
Steroidal compounds having a 17-(3-pyridyl) substituent together with a 16,17-double bond have been synthesized, using a… (More)
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Highly Cited
1994
Highly Cited
1994
Medical or surgical castration for the treatment of prostatic cancers prevents androgen production by the testes, but not by the… (More)
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Review
1994
Review
1994
The human P450c17 alpha gene (CYP17) is a single copy gene located in chromosome 10, consisting of 8 exons and 7 introns. 17… (More)
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1993
1993
Cytochrome P450c17 (EC 1.14.99.9) catalyzes both 17 alpha-hydroxylase and 17,20-lyase activities in mammalian steroidogenesis and… (More)
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Highly Cited
1991
Highly Cited
1991
When the cDNA encoding bovine microsomal 17 alpha-hydroxylase cytochrome P450 (P45017 alpha) containing modifications within the… (More)
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Highly Cited
1987
Highly Cited
1987
P450c17 is a single cytochrome P450 enzyme mediating both 17 alpha-hydroxylase and 17,20 lyase activities in the biosynthesis of… (More)
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Highly Cited
1987
Highly Cited
1987
P450c17 is the single enzyme mediating both 17 alpha-hydroxylase (steroid 17 alpha-monooxygenase, EC 1.14.99.9) and 17,20 lyase… (More)
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