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Steroid 17-alpha-Hydroxylase

Known as: alpha 17 hydroxylase, Steroid 17 alpha Hydroxylase, CYP17 
A microsomal cytochrome P450 enzyme that catalyzes the 17-alpha-hydroxylation of progesterone or pregnenolone and subsequent cleavage of the residual… 
National Institutes of Health

Related topics

Related topics

22 relations
CYP17A1 geneCYP17A1 wt AlleleCongenital adrenal hyperplasiaEnzyme Gene

Broader (2)

Cytochrome P450 Family 17Oxygenases

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
1993
Highly Cited
1993
Progesterone 16 alpha-hydroxylase activity is catalyzed by human cytochrome P450 17 alpha-hydroxylase.
Progesterone and pregnenolone are metabolized to 17 alpha-hydroxysteroids by a cytochrome P450-dependent 17 alpha-hydroxylase… 
Highly Cited
1992
Highly Cited
1992
Methane monooxygenase component B and reductase alter the regioselectivity of the hydroxylase component-catalyzed reactions. A novel role for protein-protein interactions in an oxygenase mechanism.
Highly Cited
1987
Highly Cited
1987
Testosterone inhibits cAMP-induced de Novo synthesis of Leydig cell cytochrome P-450(17 alpha) by an androgen receptor-mediated mechanism.
Highly Cited
1983
Highly Cited
1983
Calcium-evoked secretion from digitonin-permeabilized adrenal medullary chromaffin cells.
Highly Cited
1978
Highly Cited
1978
Steroid and gonadotropin levels during the luteal-follicular shift of the cyclic hamster.
This study was designed to correlate ovarian and hormonal changes of cyclic hamsters during the period of luteal regression and… 
Highly Cited
1977
Highly Cited
1977
Receptor-mediated uptake of low density lipoprotein and utilization of its cholesterol for steroid synthesis in cultured mouse adrenal cells.
Highly Cited
1975
Highly Cited
1975
A reliable, sensitive, and convenient radioactive assay for benzpyrene monooxygenase.
Highly Cited
1967
Highly Cited
1967
Pesticide-induced Enzyme Breakdown of Steroids in Birds
WIDESPREAD and severe decreases in the population of several species of birds of prey have been noted in both North America and… 
Highly Cited
1964
Highly Cited
1964
IMMUNOLOGIC STUDIES IN HUMAN ORGAN TRANSPLANTATION
Twenty-eight patients with chronic renal diseases and uremia were investigated with respect to their cutaneous responsiveness to… 
Highly Cited
1958
Highly Cited
1958
Separation of steroid sulfokinases.
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