CYP17A1 gene

Known as: CYP17, S17AH, CYTOCHROME P450, SUBFAMILY XVII 
This gene plays a role in the metabolism of estrogen and glucocorticoids. It is also involved in sexual maturation.
National Institutes of Health

Papers overview

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2013
2013
STUDY QUESTION Does fibrin introduced into the extracellular matrix affect the growth and maturation of individual primate… (More)
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Review
2008
Review
2008
A period of oocyte growth is followed by a process called oocyte maturation (the resumption of meiosis) which occurs prior to… (More)
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2007
2007
AbstractA single T > C change at the 5′ promoter region of the CYP17 gene is reported to be associated with increased risk of… (More)
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2003
2003
The CYP17 gene encodes the enzyme cytochrome P450c17alpha, which mediates both 17alpha-hydroxylase and 17,20-lyase activity in… (More)
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2002
2002
Inter-individual differences in susceptibility to breast cancer are partially mediated through the levels of endogenous and… (More)
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2001
2001
Androgen biosynthesis requires 3beta-hydroxysteroid dehydrogenase type II (3betaHSDII) and the 17alpha-hydroxylase and 17,20… (More)
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Highly Cited
1999
Highly Cited
1999
The A2 allele of CYP17 has been associated with polycystic ovarian syndrome, elevated levels of certain steroid hormones in… (More)
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1998
1998
In addition to their endogenous roles as an activation system for various Escherichia coli metabolic pathways, the soluble… (More)
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Highly Cited
1998
Highly Cited
1998
In the biosynthesis of steroid hormones, P450c17 is the single enzyme that catalyzes both the 17alpha-hydroxylation of 21-carbon… (More)
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Highly Cited
1987
Highly Cited
1987
P450c17 is a single cytochrome P450 enzyme mediating both 17 alpha-hydroxylase and 17,20 lyase activities in the biosynthesis of… (More)
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