CYP17A1 wt Allele

Known as: Cytochrome P450, Family 17, Subfamily A, Polypeptide 1 wt Allele, S17AH, CYP17 
Human CYP17A1 wild-type allele is located in the vicinity of 10q24.3 and is approximately 7 kb in length. This allele, which encodes cytochrome P450… (More)
National Institutes of Health

Papers overview

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2009
2009
CONTEXT P450 oxidoreductase (POR) deficiency causes disordered steroidogenesis; severe mutations cause genital ambiguity in both… (More)
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2004
2004
Androgens are an integral part of human physiology. The de novo production of androgens is generally limited to the adrenal… (More)
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2004
2004
We report studies on the second pregnancy of a woman who had previously given birth to a virilized female infant. The cause of… (More)
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2003
2003
Cytochrome P450c17 catalyzes 17 alpha-hydroxylation needed for cortisol synthesis and 17,20 lyase activity needed to produce sex… (More)
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2002
2002
Because some studies have linked polymorphic variants of the estrogen-metabolizing genes CYP17 and catechol O-methyl transferase… (More)
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2000
2000
The present study was conducted to reveal effects of in ovo injection of nonsteroidal aromatase inhibitor (Fadrozole) or… (More)
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1999
1999
Biochemical studies suggest that 17,20-lyase activity, and thus efficient synthesis of androgens by human P450c17, requires both… (More)
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Highly Cited
1998
Highly Cited
1998
In the biosynthesis of steroid hormones, P450c17 is the single enzyme that catalyzes both the 17alpha-hydroxylation of 21-carbon… (More)
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Review
1997
Review
1997
P450c17 is a single microsomal enzyme that catalyzes two distinct steroid biosynthetic activities: 17 alpha-hydroxylase and 17,20… (More)
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1993
1993
Cytochrome P450c17 (EC 1.14.99.9) catalyzes both 17 alpha-hydroxylase and 17,20-lyase activities in mammalian steroidogenesis and… (More)
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