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CYP17A1 wt Allele

Known as: Cytochrome P450, Family 17, Subfamily A, Polypeptide 1 wt Allele, S17AH, CYP17 
Human CYP17A1 wild-type allele is located in the vicinity of 10q24.3 and is approximately 7 kb in length. This allele, which encodes cytochrome P450… Expand
National Institutes of Health

Papers overview

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Highly Cited
2008
Highly Cited
2008
P450 oxidoreductase (POR) is an electron-donating flavoprotein required for the activity of all microsomal cytochrome P450… Expand
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Highly Cited
2005
Highly Cited
2005
Cytochrome P450c17 catalyzes the 17α-hydroxylase activity required for glucocorticoid synthesis and the 17,20 lyase activity… Expand
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Highly Cited
2001
Highly Cited
2001
Androgen biosynthesis requires 3β-hydroxysteroid dehydrogenase type II (3βHSDII) and the 17α-hydroxylase and 17,20-lyase… Expand
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Highly Cited
1999
Highly Cited
1999
Cytochrome P450c17 catalyzes steroid 17alpha-hydroxylase and 17,20-lyase activities and hence is a key enzyme in the production… Expand
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Highly Cited
1998
Highly Cited
1998
In the biosynthesis of steroid hormones, P450c17 is the single enzyme that catalyzes both the 17α-hydroxylation of 21-carbon… Expand
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Review
1997
Review
1997
P450c17 is a single microsomal enzyme that catalyzes two distinct steroid biosynthetic activities: 17 alpha-hydroxylase and 17,20… Expand
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Highly Cited
1995
Highly Cited
1995
Neurosteroids are steroids that are synthesized de novo in the brain and include some classical (adrenal and gonadal steroids… Expand
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Highly Cited
1993
Highly Cited
1993
To determine if neurosteroids (steroids synthesized in the brain) are produced by enzymes found in steroidogenic tissues, we… Expand
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Highly Cited
1987
Highly Cited
1987
P450c17 is the single enzyme mediating both 17 alpha-hydroxylase (steroid 17 alpha-monooxygenase, EC 1.14.99.9) and 17,20 lyase… Expand
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Highly Cited
1987
Highly Cited
1987
P450c17 is a single cytochrome P450 enzyme mediating both 17 alpha-hydroxylase and 17,20 lyase activities in the biosynthesis of… Expand
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