Steroid 11-beta-Monooxygenase

Known as: Cytochrome P-450(11 beta), Steroid 11-Beta-Hydroxylase, Steroid 11 beta Hydroxylase 
A mitochondrial cytochrome P450 enzyme that catalyzes the 11-beta-hydroxylation of steroids in the presence of molecular oxygen and NADPH… (More)
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
CONTEXT Aldosterone synthase (CYP11B2) and steroid 11 beta-hydroxylase (CYP11B1) catalyze the terminal steps for aldosterone and… (More)
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Review
2008
Review
2008
The recent discovery--from a meta-analysis of 18 randomized controlled trials--that supplemental cholecalciferol (vitamin D… (More)
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Highly Cited
2003
Highly Cited
2003
We report on the production of hydrocortisone, the major adrenal glucocorticoid of mammals and an important intermediate of… (More)
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Review
2001
Review
2001
A plasticity of gonadal sex differentiation was reported in the 1930s following exogenous steroid treatments in fish, but… (More)
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Highly Cited
1992
Highly Cited
1992
We proposed that a cell-selective regulatory protein coordinately regulates the expression of three enzymes that are required for… (More)
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Highly Cited
1992
Highly Cited
1992
Sera from patients with idiopathic Addison's disease commonly react with the zona glomerulosa of adrenal cortex. We used high… (More)
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Highly Cited
1992
Highly Cited
1992
Patients with glucocorticoid-remediable aldosteronism (GRA) from 12 kindreds possess chimaeric gene duplications arising from… (More)
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Highly Cited
1990
Highly Cited
1990
We established a continuous cell line, NCI-H295, from an invasive primary adrenocortical carcinoma. The cell line was established… (More)
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Highly Cited
1989
Highly Cited
1989
Steroid 11 beta-hydroxylase (P-450(11) beta) is a mitochondrial cytochrome P-450 enzyme necessary for cortisol biosynthesis… (More)
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Highly Cited
1984
Highly Cited
1984
The use of the intravenous anesthetic etomidate for prolonged sedation has been associated with low levels of plasma cortisol and… (More)
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