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Steroid 11-beta-Monooxygenase
Known as:
Cytochrome P-450(11 beta)
, Steroid 11-Beta-Hydroxylase
, Steroid 11 beta Hydroxylase
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A mitochondrial cytochrome P450 enzyme that catalyzes the 11-beta-hydroxylation of steroids in the presence of molecular oxygen and NADPH…
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National Institutes of Health
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Related topics
Related topics
26 relations
Adrenogenital Syndrome
Aldosterone Synthase
CYP11B1 gene
CYP11B1 wt Allele
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Narrower (1)
Cyp11c1 protein, zebrafish
Broader (2)
Cytochrome P450
Oxygenases
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Review
2006
Review
2006
CYP17- and CYP11B-dependent steroid hydroxylases as drug development targets.
T. Hakki
,
R. Bernhardt
Pharmacology and Therapeutics
2006
Corpus ID: 203998
Highly Cited
2001
Highly Cited
2001
Liver receptor homologue-1 is expressed in the adrenal and can regulate transcription of 11 beta-hydroxylase.
ZN Wang
,
M. Bassett
,
W. E. Rainey
Journal of Molecular Endocrinology
2001
Corpus ID: 6439422
Liver receptor homologue-1 (LRH-1, designated NR5A2) is a mammalian homologue of Drosophila fushi tarazu factor (dFTZ-F1) and…
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Highly Cited
1996
Highly Cited
1996
Gene conversion in the CYP11B2 gene encoding P450c11AS is associated with, but does not cause, the syndrome of corticosterone methyloxidase II deficiency.
C E Fardella
,
D W Hum
,
+5 authors
W L Miller
Journal of Clinical Endocrinology and Metabolism
1996
Corpus ID: 46332169
Cytochrome P450c11AS (aldosterone synthase) has 11 beta-hydroxylase, 18-hydroxylase, and 18-oxidase activities and is expressed…
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1988
1988
Expression of two kinds of cytochrome P-450(11 beta) mRNA in bovine adrenal cortex.
S. Kirita
,
K. Morohashi
,
T. Hashimoto
,
H. Yoshioka
,
Y. Fujii‐Kuriyama
,
T. Omura
Journal of Biochemistry (Tokyo)
1988
Corpus ID: 3154819
Using pcP-450(11 beta)-2 cDNA (Morohashi et al. (1987) J. Biochem. 102, 559-568) as the probe, a different cDNA clone, pcP-450(11…
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Highly Cited
1987
Highly Cited
1987
Aldosterone biosynthesis and cytochrome P-45011 beta: evidence for two different forms of the enzyme in rats.
M. Lauber
,
S. Sugano
,
T. Ohnishi
,
M. Okamoto
,
J. Müller
Journal of Steroid Biochemistry
1987
Corpus ID: 40705181
Highly Cited
1985
Highly Cited
1985
Molecular cloning and amino acid sequence of the precursor form of bovine adrenodoxin: evidence for a previously unidentified COOH-terminal peptide.
T. Okamura
,
M. John
,
M. X. Zuber
,
E. Simpson
,
M. Waterman
Proceedings of the National Academy of Sciences…
1985
Corpus ID: 22472685
Several recombinant cDNA clones specific for the mitochondrial iron-sulfur protein adrenodoxin have been identified in a bovine…
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Highly Cited
1984
Highly Cited
1984
Induction of synthesis of mitochondrial steroidogenic enzymes of bovine adrenocortical cells by analogs of cyclic AMP.
Robert E. KramerSQ
,
William E. Raineyy
,
Bruria Funkensteinll
,
Albert Dee
,
Evan R. SimpsonSII
,
Michael R. Waterman
Journal of Biological Chemistry
1984
Corpus ID: 32526997
Review
1981
Review
1981
Genetic mechanisms controlling the induction of polysubstrate monooxygenase (P-450) activities.
D. Nebert
,
H. Eisen
,
M. Negishi
,
M. Lang
,
L. Hjelmeland
,
A. Okey
Annual Review of Pharmacology and Toxicology
1981
Corpus ID: 12545408
Highly Cited
1969
Highly Cited
1969
Submitochondrial distribution of components of the steroid 11 beta-hydroxylase and cholesterol sidechain-cleaving enzyme systems in hog adrenal cortex.
N. Yago
,
S. Ichii
Journal of Biochemistry (Tokyo)
1969
Corpus ID: 9456907
Highly Cited
1965
Highly Cited
1965
Hemoprotein content and activity of solubilized steroid 11 beta-hydroxylase preparations from adrenocortical mitochondria.
David Y. Cooper
,
S. Narasimhulu
,
A. Slade
,
W. Raich
,
O. Foroff
,
Otto Rosenthal
Life Science
1965
Corpus ID: 10011423
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