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Steroid 11-beta-Monooxygenase

Known as: Cytochrome P-450(11 beta), Steroid 11-Beta-Hydroxylase, Steroid 11 beta Hydroxylase 
A mitochondrial cytochrome P450 enzyme that catalyzes the 11-beta-hydroxylation of steroids in the presence of molecular oxygen and NADPH… 
National Institutes of Health

Related topics

Related topics

26 relations
Adrenogenital SyndromeAldosterone SynthaseCYP11B1 geneCYP11B1 wt Allele

Narrower (1)

Cyp11c1 protein, zebrafish

Broader (2)

Cytochrome P450Oxygenases

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2006
Review
2006
CYP17- and CYP11B-dependent steroid hydroxylases as drug development targets.
Highly Cited
2001
Highly Cited
2001
Liver receptor homologue-1 is expressed in the adrenal and can regulate transcription of 11 beta-hydroxylase.
Liver receptor homologue-1 (LRH-1, designated NR5A2) is a mammalian homologue of Drosophila fushi tarazu factor (dFTZ-F1) and… 
Highly Cited
1996
Highly Cited
1996
Gene conversion in the CYP11B2 gene encoding P450c11AS is associated with, but does not cause, the syndrome of corticosterone methyloxidase II deficiency.
Cytochrome P450c11AS (aldosterone synthase) has 11 beta-hydroxylase, 18-hydroxylase, and 18-oxidase activities and is expressed… 
1988
1988
Expression of two kinds of cytochrome P-450(11 beta) mRNA in bovine adrenal cortex.
Using pcP-450(11 beta)-2 cDNA (Morohashi et al. (1987) J. Biochem. 102, 559-568) as the probe, a different cDNA clone, pcP-450(11… 
Highly Cited
1987
Highly Cited
1987
Aldosterone biosynthesis and cytochrome P-45011 beta: evidence for two different forms of the enzyme in rats.
Highly Cited
1985
Highly Cited
1985
Molecular cloning and amino acid sequence of the precursor form of bovine adrenodoxin: evidence for a previously unidentified COOH-terminal peptide.
Several recombinant cDNA clones specific for the mitochondrial iron-sulfur protein adrenodoxin have been identified in a bovine… 
Highly Cited
1984
Highly Cited
1984
Induction of synthesis of mitochondrial steroidogenic enzymes of bovine adrenocortical cells by analogs of cyclic AMP.
Review
1981
Review
1981
Genetic mechanisms controlling the induction of polysubstrate monooxygenase (P-450) activities.
Highly Cited
1969
Highly Cited
1969
Submitochondrial distribution of components of the steroid 11 beta-hydroxylase and cholesterol sidechain-cleaving enzyme systems in hog adrenal cortex.
Highly Cited
1965
Highly Cited
1965
Hemoprotein content and activity of solubilized steroid 11 beta-hydroxylase preparations from adrenocortical mitochondria.
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