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CYP11B1 wt Allele

Known as: P450C11, CYP11B, FHI 
Human CYP11B1 wild-type allele is located within 8q21 and is approximately 7 kb in length. This allele, which encodes cytochrome P450 11B1… 
National Institutes of Health

Related topics

Related topics

12 relations
8q21Adrenal Cortical HyperplasiaCYP11B2 geneCYP11B2 wt Allele

Broader (1)

CYP11B1 gene

Papers overview

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Highly Cited
2007
Highly Cited
2007
Construction of 3D models of the CYP11B family as a tool to predict ligand binding characteristics
Aldosterone is synthesised by aldosterone synthase (CYP11B2). CYP11B2 has a highly homologous isoform, steroid 11β-hydroxylase… 
Highly Cited
2007
Highly Cited
2007
Epidemiologic relationship between fuchs heterochromic iridocyclitis and the United States rubella vaccination program.
Highly Cited
2003
Highly Cited
2003
Atomic oxygen species on silver: Photoelectron spectroscopy and x-ray absorption studies
Two oxygen species, which are constituents of the active centers for ethylene epoxidation over silver, have been characterized by… 
Highly Cited
2000
Highly Cited
2000
Transcriptional Regulation of Human 11β-Hydroxylase (hCYP11B1).
Steroid 11β-hydroxylase is a mitochondrial enzyme that catalyzes the conversion of deoxycortisol to cortisol. The gene encoding… 
Review
1999
Review
1999
Peer education and HIV / AIDS : Concepts , uses and challenges
All rights reserved.This document,which is not a formal publication of UNAIDS,may be freely reviewed,quoted, reproduced or… 
Highly Cited
1998
Highly Cited
1998
Recombinant CYP11B genes encode enzymes that can catalyze conversion of 11-deoxycortisol to cortisol, 18-hydroxycortisol, and 18-oxocortisol.
CYP11B1 (11beta-hydroxylase) and CYP11B2 (aldosterone synthase) are 93% identical mitochondrial enzymes that both catalyze 11beta… 
Highly Cited
1995
Highly Cited
1995
P450c11B3 mRNA, Transcribed from a Third P450c11 Gene, Is Expressed in a Tissue-specific, Developmentally, and Hormonally Regulated Fashion in the Rodent Adrenal and Encodes a Protein with Both 11…
The rat genome contains four P450c11 genes. One of these (CYP11B1) encodes P450c11β, which is the steroid 11β-hydroxylase found… 
Highly Cited
1995
Highly Cited
1995
Novel Involvement of a Mitochondrial Steroid Hydroxylase (P450c11) in Xenobiotic Metabolism (*)
Adrenocortical mitochondrial cytochrome P450 isozymes of the Cyp11 family normally synthesize steroids with a very strict… 
Highly Cited
1993
Highly Cited
1993
Activation of CYP11A and CYP11B gene promoters by the steroidogenic cell-specific transcription factor, Ad4BP.
We have examined the transcriptional activity of four cis-elements, Ad1(CRE), Ad2, Ad3, and Ad4, that are present in the promoter… 
Highly Cited
1993
Highly Cited
1993
Isolation and characterization of rat CYP11B genes involved in late steps of mineralo- and glucocorticoid syntheses.
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