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CYP11B2 wt Allele

Known as: CPN2, CYP11BL, Cytochrome P450, Family 11, Subfamily B, Polypeptide 2 wt Allele 
Human CYP11B2 wild-type allele is located within 8q21-q22 and is approximately 7 kb in length. This allele, which encodes cytochrome P450 11B2… Expand
National Institutes of Health

Papers overview

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2007
2007
Aldosterone is synthesised by aldosterone synthase (CYP11B2). CYP11B2 has a highly homologous isoform, steroid 11β-hydroxylase… Expand
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Review
2006
Review
2006
Steroid hormone biosynthesis is catalyzed by the action of a series of cytochrome P450 enzymes as well as reductases. Defects in… Expand
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2002
2002
In this study we describe the isolation of three genes of the CYP11B family of the guinea pig. CYP11B1 codes for the previously… Expand
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Highly Cited
1998
Highly Cited
1998
In an attempt to identify proteins that might underlie membrane trafficking processes in ciliates, calcium-dependent… Expand
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1996
1996
In humans the last steps in the synthesis of aldosterone and cortisol rely on the activity of two cytochrome P450 genes termed… Expand
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Highly Cited
1995
Highly Cited
1995
Glucocorticoid-suppressible hyperaldosteronism is a dominantly inherited form of hypertension believed to be caused by the… Expand
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Review
1994
Review
1994
The most active corticosteroids are 11 beta-hydroxylated. Humans have two isozymes with 11 beta-hydroxylase activity that are… Expand
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Highly Cited
1994
Highly Cited
1994
Ad4BP, a zinc finger DNA-binding protein, was identified as a transcription factor regulating steroidogenic P-450 genes in a cAMP… Expand
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Highly Cited
1993
Highly Cited
1993
We have examined the transcriptional activity of four cis-elements, Ad1(CRE), Ad2, Ad3, and Ad4, that are present in the promoter… Expand
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Highly Cited
1992
Highly Cited
1992
Glucocorticoid-suppressible hyperaldosteronism (GSH) is an autosomal dominant form of familial hypertension. The biochemical… Expand
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