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CYP11B2 wt Allele

Known as: CPN2, CYP11BL, Cytochrome P450, Family 11, Subfamily B, Polypeptide 2 wt Allele 
Human CYP11B2 wild-type allele is located within 8q21-q22 and is approximately 7 kb in length. This allele, which encodes cytochrome P450 11B2… 
National Institutes of Health

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8q21-q22CYP11B1 geneCYP11B1 wt AlleleCYP11B2 protein, human

Broader (1)

CYP11B2 gene

Papers overview

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2010
2010
The onset of cortisol synthesis and the stress response is independent of changes in CYP11B or CYP21 mRNA levels in larval red drum (Sciaenops ocellatus).
Review
2009
Review
2009
Cushing's syndrome by left adrenocortical adenoma synchronously associated with primary aldosteronism by right adrenocortical adenoma: report of a case.
Synchronous associations of Cushing's syndrome (CS) and primary aldosteronism (PA) with multiple adrenocortical adenomas… 
Review
2006
Review
2006
CYP17- and CYP11B-dependent steroid hydroxylases as drug development targets.
2000
2000
Regulation of Human CYP11B2 and CYP11B1: Comparing the Role of the Common CRE/Ad1 Element
In humans, the final steps in corticosteroid production results from the activity of aldosterone synthase in the glomerulosa and… 
2000
2000
Two Novel Mutations in Splice Donor Sites of CYP11B1 in Congenital Adrenal Hyperplasia Due to 11β-Hydroxylase Deficiency
We present an in vivo and in vitro study of congenital adrenal hyperplasia in a patient with 11β-hydroxylase deficiency. Genetic… 
1999
1999
Interaction of CYP11B1 (cytochrome P-45011 beta) with CYP11A1 (cytochrome P-450scc) in COS-1 cells.
The interactions of CYP11B1 (cytochrome P-45011beta), CYP11B2 (cytochrome P-450aldo) and CYP11A1 (cytochrome P-450scc) were… 
1996
1996
Molecular cloning and functional expression of the cytochrome P450 11B-hydroxylase of the guinea pig.
Abstract A cDNA library has been constructed from adrenal glands of guinea pigs receiving a low sodium/high potassium diet. From… 
1995
1995
Zona fasciculata-like cells determine the response of plasma aldosterone to metoclopramide and aldosterone synthase messenger ribonucleic acid level in aldosterone-producing adenoma.
The different responses of plasma aldosterone to ACTH and angiotensin II in aldosterone-producing adenoma (APA) is thought to be… 
Review
1993
Review
1993
Twin genes and endocrine disease: CYP21 and CYP11B genes.
CYP21 and CYP11B genes have a common feature: they are "twin" genes. It seems as if doubling and subsequent drifting apart… 
Review
1981
Review
1981
Is aldosterone secretion under dopaminergic control?
ALTHOUGH angiotensin, potassium, sodium, and adrenocorticotrophic hormone are generally acknowledged as major direct influences… 
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