Spinocerebellar Ataxia Type 2

Spinocerebellar ataxia type 2 (SCA2) is an autosomal dominantly inherited, neurodegenerative disease caused by an expansion of… (More)

To study the use of transcranial brain parenchyma sonography (TCS), in particular the echogenic signal in the substantia nigra… (More)

Patients with spinocerebellar ataxia type 2 (SCA2), develop severe pontine nuclei, inferior olives, and Purkinje cell… (More)

BACKGROUND Autosomal dominant spinocerebellar ataxia type 2 (SCA2) bears clinical and neuropathologic similarities to sporadic… (More)

BACKGROUND We recently reported that spinocerebellar ataxia type 2 (SCA2) caused familial parkinsonism in 2 brothers with… (More)

Cognitive impairment was studied in distinct types of spinocerebellar ataxia (SCA): eleven SCA1, 14 SCA2, and 11 SCA3 individuals… (More)

OBJECTIVE To describe the clinical and molecular genetic analysis of a large family of northern Chinese descent with a mutation… (More)

The gene for spinocerebellar ataxia type 2 (SCA2) has been mapped to 12q24.1. A1.1–megabase contig in the candidate region was… (More)

Spinocerebellar ataxia type 2 (SCA2) is an autosomal dominant, neurodegenerative disorder that affects the cerebellum and other… (More)

Patients with spinocerebellar ataxia 3 (SCA3) and Machado-Joseph disease (MJD) carry an expanded CAG repeat in the MJD1 gene. One… (More)