Ataxia, Spinocerebellar

Known as: Dominantly-Inherited Spinocerebellar Ataxias, Spinocerebellar Ataxias, Dominantly Inherited, Spinocerebellar Degeneration 
A group of dominantly inherited, predominately late-onset, cerebellar ataxias which have been divided into multiple subtypes based on clinical… (More)
National Institutes of Health

Papers overview

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Highly Cited
2006
Highly Cited
2006
OBJECTIVE To develop a reliable and valid clinical scale measuring the severity of ataxia. METHODS The authors devised the… (More)
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Highly Cited
2006
Highly Cited
2006
We previously reported that a (CTG)n expansion causes spinocerebellar ataxia type 8 (SCA8), a slowly progressive ataxia with… (More)
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Highly Cited
2004
Highly Cited
2004
The dominant polyglutamine expansion diseases, which include spinocerebellar ataxia type 1 (SCA1) and Huntington disease, are… (More)
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Review
2004
Review
2004
Autosomal dominant cerebellar ataxias are hereditary neurodegenerative disorders that are known as spinocerebellar ataxias (SCA… (More)
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Highly Cited
1999
Highly Cited
1999
Myotonic dystrophy (DM) is the only disease reported to be caused by a CTG expansion. We now report that a non-coding CTG… (More)
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Highly Cited
1997
Highly Cited
1997
The mechanism of neurodegeneration in CAG/polyglutamine repeat expansion diseases is unknown but is thought to occur at the… (More)
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Highly Cited
1996
Highly Cited
1996
The gene for spinocerebellar ataxia type 2 (SCA2) has been mapped to 12q24.1. A1.1–megabase contig in the candidate region was… (More)
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Highly Cited
1996
Highly Cited
1996
Two forms of the neurodegenerative disorder spinocerebellar ataxia are known to be caused by the expansion of a CAG… (More)
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Highly Cited
1996
Highly Cited
1996
Spinocerebellar ataxia type 2 (SCA2) is an autosomal dominant, neurodegenerative disorder that affects the cerebellum and other… (More)
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Highly Cited
1993
Highly Cited
1993
Spinocerebellar ataxia type 1 (SCA1) is an autosomal dominant disorder characterized by neurodegeneration of the cerebellum… (More)
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