Spinal cord posterior horn

Chronic pain, both inflammatory and neuropathic, is a debilitating condition in which the pain experience persists after the… Expand

Neuropathic pain that occurs after peripheral nerve injury depends on the hyperexcitability of neurons in the dorsal horn of the… Expand

Synaptic plasticity is fundamental to many neurobiological functions, including memory and pain. Central sensitization refers to… Expand

Modern pain-control theory predicts that a loss of inhibition (disinhibition) in the dorsal horn of the spinal cord is a crucial… Expand

The peptide neurotransmitter substance P modulates sensitivity to pain by activating the neurokinin-1 (NK-1) receptor, which is… Expand

Pain can be effectively diminished by various endogenous mechanisms within the central nervous system. One region where these… Expand

&NA; The formalin test for nociception, which is predominantly used with rats and mice, involves moderate, continuous pain… Expand

A potent, synthetic cannabinoid was radiolabeled and used to characterize and precisely localize cannabinoid receptors in slide… Expand

The distribution of cells that express mRNA encoding the androgen (AR) and estrogen (ER) receptors was examined in adult male and… Expand

It has been suggested that the proto-oncogenes c-fos and c-myc participate in the control of genetic events which lead to the… Expand