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Spermidine/Spermine N1-Acetyltransferase

Known as: spermidine-spermine N(1)-acetyltransferase, spermidine acetyltransferase, cSAT transferase 
National Institutes of Health

Related topics

Related topics

7 relations

Broader (2)

AcetyltransferaseAcyltransferase
SAT1 geneSAT1 wt AlleleSLC26A1 gene

Narrower (2)

SAT1 protein, humanSat2 protein, mouse

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
Proximal Tubule Epithelial Cell Specific Ablation of the Spermidine/Spermine N1-Acetyltransferase Gene Reduces the Severity of Renal Ischemia/Reperfusion Injury
Background Expression and activity of spermidine/spermine N1-acetyltransferase (SSAT) increases in kidneys subjected to ischemia… 
Review
2006
Review
2006
Genetic manipulation of polyamine catabolism in rodents.
Activation of polyamine catabolism through the overexpression of spermidine/spermine N1-acetyltransferase (SSAT) in transgenic… 
2003
2003
Small interfering RNA suppression of polyamine analog-induced spermidine/spermine n1-acetyltransferase.
N1,N11-diethylnorspermine (DENSPM) is a polyamine analog that down-regulates polyamine biosynthesis and potently upregulates the… 
Highly Cited
2003
Highly Cited
2003
Expression of SSAT, a novel biomarker of tubular cell damage, increases in kidney ischemia-reperfusion injury.
Ischemia-reperfusion injury (IRI) is the major cause of acute renal failure in native and allograft kidneys. Identifying the… 
2003
2003
Properties of the Spermidine/SpermineN 1-Acetyltransferase Mutant L156F That Decreases Cellular Sensitivity to the Polyamine AnalogueN 1,N 11-Bis(ethyl)norspermine*
Properties of a mutant form of spermidine/spermine N 1-acetyltransferase, L156F (L156F-SSAT), that is present in Chinese hamster… 
Highly Cited
2001
Highly Cited
2001
Polyamine analogues inhibit the ubiquitination of spermidine/spermine N1-acetyltransferase and prevent its targeting to the proteasome for degradation.
Spermidine/spermine N(1)-acetyltransferase (SSAT), a key enzyme in mammalian polyamine catabolism, undergoes rapid turnover (half… 
Highly Cited
1998
Highly Cited
1998
The Identification of a Cis-element and a Trans-acting Factor Involved in the Response to Polyamines and Polyamine Analogues in the Regulation of the Human Spermidine/Spermine N 1-Acetyltransferase…
The superinduction of spermidine/spermineN 1-acetyltransferase (SSAT) gene has been associated with a cytotoxic response to a new… 
1982
1982
Induction of spermidine N1-acetyltransferase by dialkylnitrosamines.
Treatment of rats with dimethylnitrosamine (30 mg/kg) or diethylnitrosamine (200 mg/kg) produced a rapid increase in the activity… 
Review
1982
Review
1982
Induction of spermidine N 1‐acetyltransferase in rat kidney by treatment with folic acid
1975
1975
Specific inhibition of ouabain sensitive and K+-dependent p-nitrophenylphosphatase by polyamines.
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