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Solute Carrier Family 12, Member 3
Known as:
SLC12A3 Protein
, Na Cl Cotransporter
, Cotransporter, Na-Cl Thiazide-Sensitive
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Na-Cl cotransporter in the convoluted segments of the DISTAL KIDNEY TUBULE. It mediates active reabsorption of sodium and chloride and is inhibited…
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National Institutes of Health
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Related topics
Related topics
11 relations
Gitelman Syndrome
In Blood
Process of secretion
SLC12A3 gene
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Broader (1)
Sodium Chloride Symporters
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Review
2018
Review
2018
Molecular Identities and ATP Release Activities of Two Types of Volume-Regulatory Anion Channels, VSOR and Maxi-Cl.
Y. Okada
,
Toshiaki Okada
,
Md. Rafiqul Islam
,
R. Sabirov
Current topics in membranes
2018
Corpus ID: 52350988
Review
2009
Review
2009
Regulation of magnesium reabsorption in DCT
Qi Xi
,
J. Hoenderop
,
R. Bindels
Pflügers Archiv: European Journal of Physiology
2009
Corpus ID: 8742907
The distal convoluted tubule (DCT) is the shortest segment of the nephron and consists of an early (DCT1) and late part (DCT2…
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Highly Cited
2006
Highly Cited
2006
Affinity-defining Domains in the Na-Cl Cotransporter
Erika Moreno
,
P. Cristóbal
,
Manuel Rivera
,
Norma Vázquez
,
N. Bobadilla
,
G. Gamba
Journal of Biological Chemistry
2006
Corpus ID: 26090914
The thiazide-sensitive Na+-Cl- cotransporter (NCC) is the major pathway for salt reabsorption in the distal convoluted tubule…
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2004
2004
Antibacterial Titanium Plate Anodized by being Discharged in NaCl Solution Exhibits Cell Compatibility
Y. Shibata
,
H. Kawai
,
H. Yamamoto
,
T. Igarashi
,
T. Miyazaki
Journal of dentistry research
2004
Corpus ID: 21515553
Implant surfaces should be modified to achieve excellent cell compatibility as well as antibacterial activity. Our previous study…
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2002
2002
Interaction with grp58 increases activity of the thiazide-sensitive Na-Cl cotransporter.
B. Wyse
,
N. Ali
,
D. Ellison
AJP - Renal Physiology
2002
Corpus ID: 25504815
The thiazide-sensitive sodium-chloride cotransporter (NCC) is expressed by distal convoluted tubule cells of the mammalian kidney…
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Highly Cited
2000
Highly Cited
2000
Dependence of KCC2 K-Cl cotransporter activity on a conserved carboxy terminus tyrosine residue.
K. Strange
,
T. D. Singer
,
R. Morrison
,
E. Delpire
American Journal of Physiology - Cell Physiology
2000
Corpus ID: 18500910
K-Cl cotransporters (KCC) play fundamental roles in ionic and osmotic homeostasis. To date, four mammalian KCC genes have been…
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Highly Cited
2000
Highly Cited
2000
Novel mutations in thiazide-sensitive Na-Cl cotransporter gene of patients with Gitelman's syndrome.
T. Monkawa
,
I. Kurihara
,
Kazuo Kobayashi
,
M. Hayashi
,
T. Saruta
Journal of the American Society of Nephrology
2000
Corpus ID: 20405920
Gitelman's syndrome (GS) is an autosomal recessive disorder characterized by metabolic alkalosis, hypokalemia, hypomagnesemia…
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2000
2000
The transport properties of the human renal Na(+)- dicarboxylate cotransporter under voltage-clamp conditions.
X. Yao
,
A. Pajor
AJP - Renal Physiology
2000
Corpus ID: 13201235
The transport properties of the human Na(+)-dicarboxylate cotransporter, (hNaDC-1), expressed in Xenopus laevis oocytes were…
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Highly Cited
1996
Highly Cited
1996
Linkage of Gitelman syndrome to the thiazide-sensitive sodium-chloride cotransporter gene with identification of mutations in Dutch families
H. Lemmink
,
L. P. Van den Heuvel
,
+6 authors
N. Knoers
Pediatric nephrology (Berlin, West)
1996
Corpus ID: 9591584
Abstract. Gitelman syndrome is a mostly autosomal recessive disorder affecting the renal tubular function associated with…
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Highly Cited
1994
Highly Cited
1994
Structural implications for the role of the N terminus in the ‘superactivation’ of collagenases
P. Reinemer
,
F. Grams
,
+5 authors
W. Bode
FEBS Letters
1994
Corpus ID: 2454182
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