Skip to search formSkip to main contentSkip to account menu

Sodium Chloride Symporters

Known as: Sodium Chloride Symporters [Chemical/Ingredient], Sodium Chloride Cotransporters, Na Cl Symporters 
A subclass of symporters found in KIDNEY TUBULES, DISTAL that are the major pathway for salt resorption. Inhibition of these symporters by… 
National Institutes of Health

Related topics

Related topics

12 relations
Gitelman SyndromeIn BloodProcess of secretionSLC12A3 gene

Narrower (2)

Solute Carrier Family 12, Member 3thiazide receptor

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2012
Review
2012
Mechanisms of sodium–chloride cotransporter modulation by angiotensin II
Purpose of reviewThe renin–angiotensin–aldosterone system is an important modulator of renal salt excretion and arterial pressure… 
2012
2012
Lithium interactions with Na+-coupled inorganic phosphate cotransporters: insights into the mechanism of sequential cation binding.
Type IIa/b Na(+)-coupled inorganic phosphate cotransporters (NaPi-IIa/b) are considered to be exclusively Na(+) dependent. Here… 
2010
2010
WNK4 inhibits NCC protein expression through MAPK ERK1/2 signaling pathway independent of SPAK/OSR1 pathway
WNK kinase is a subfamily of serine/threonine kinases. WNK1 and WNK4 were shown to stimulate NCC activity through SPAK and OSR1… 
2006
2006
Hypokalemic paralysis due to Gitelman syndrome: A family study
Hypokalemic paralysis is rarely seen as the presenting feature in patients with Gitelman syndrome. We report a Chinese man who… 
2003
2003
Ammonium transport and pH regulation by K (cid:1) -Cl (cid:2) cotransporters
Ammonium transport and pH regulation by K -Cl cotransporters. Am J Physiol Renal Physiol 285: F68–F78, 2003. The Na (cid:1) -K… 
2002
2002
Interaction with grp58 increases activity of the thiazide-sensitive Na-Cl cotransporter.
The thiazide-sensitive sodium-chloride cotransporter (NCC) is expressed by distal convoluted tubule cells of the mammalian kidney… 
1999
1999
Characterization of Na+/[Formula: see text]cotransporter isoform NBC-3.
Na+-[Formula: see text]cotransporters mediate the transport of[Formula: see text] into or out of the cell. Two Na+-[Formula: see… 
Highly Cited
1996
Highly Cited
1996
Linkage of Gitelman syndrome to the thiazide-sensitive sodium-chloride cotransporter gene with identification of mutations in Dutch families
Abstract. Gitelman syndrome is a mostly autosomal recessive disorder affecting the renal tubular function associated with… 
Highly Cited
1996
Highly Cited
1996
Cloning and sequencing of the monocarboxylate transporter from mouse Ehrlich Lettré tumour cell confirms its identity as MCT1 and demonstrates that glycosylation is not required for MCT1 function.
Highly Cited
1992
Highly Cited
1992
Molecular evidence for two renal Na+/glucose cotransporters.
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)