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Small Molecule
Known as:
Small molecules
A molecule with a low molecular weight that is not determined by a genome sequence.
National Institutes of Health
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Related topics
Related topics
4 relations
Broader (2)
Molecular Biology
molecular size
Nanotechnology
chemical genetics
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2012
Highly Cited
2012
Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death
S. Dixon
,
K. Lemberg
,
+9 authors
B. Stockwell
Cell
2012
Corpus ID: 206559990
Review
2012
Review
2012
Small molecule organic semiconductors on the move: promises for future solar energy technology.
A. Mishra
,
P. Bäuerle
Angewandte Chemie
2012
Corpus ID: 32760144
This article is written from an organic chemist's point of view and provides an up-to-date review about organic solar cells based…
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Highly Cited
2010
Highly Cited
2010
Structures of the CXCR4 Chemokine GPCR with Small-Molecule and Cyclic Peptide Antagonists
B. Wu
,
E. Chien
,
+12 authors
R. Stevens
Science
2010
Corpus ID: 17413172
Regulating Migration The migration of cells around the body is an important factor in cancer development and the establishment of…
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Highly Cited
2010
Highly Cited
2010
Metal-organic frameworks with functional pores for recognition of small molecules.
Banglin Chen
,
S. Xiang
,
G. Qian
Accounts of chemical research
2010
Corpus ID: 206818640
Molecular recognition, an important process in biological and chemical systems, governs the diverse functions of a variety of…
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Review
2009
Review
2009
Targeting cancer with small molecule kinase inhibitors
Jianming Zhang
,
Priscilla L. Yang
,
N. Gray
Nature Reviews Cancer
2009
Corpus ID: 17934366
Deregulation of kinase activity has emerged as a major mechanism by which cancer cells evade normal physiological constraints on…
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Highly Cited
2007
Highly Cited
2007
Small molecule activators of SIRT1 as therapeutics for the treatment of type 2 diabetes
J. Milne
,
P. Lambert
,
+25 authors
C. Westphal
Nature
2007
Corpus ID: 4398257
Calorie restriction extends lifespan and produces a metabolic profile desirable for treating diseases of ageing such as type 2…
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Highly Cited
2006
Highly Cited
2006
The Connectivity Map: Using Gene-Expression Signatures to Connect Small Molecules, Genes, and Disease
J. Lamb
,
E. Crawford
,
+17 authors
T. Golub
Science
2006
Corpus ID: 8728079
To pursue a systematic approach to the discovery of functional connections among diseases, genetic perturbation, and drug action…
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Review
2006
Review
2006
Bacterial Small-Molecule Signaling Pathways
A. Camilli
,
B. Bassler
Science
2006
Corpus ID: 35517533
Bacteria use diverse small molecules for extra- and intracellular signaling. They scan small-molecule mixtures to access…
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Highly Cited
2005
Highly Cited
2005
A small molecule–kinase interaction map for clinical kinase inhibitors
M. A. Fabian
,
W. Biggs
,
+23 authors
D. Lockhart
Nature Biotechnology
2005
Corpus ID: 7780811
Kinase inhibitors show great promise as a new class of therapeutics. Here we describe an efficient way to determine kinase…
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Review
2004
Review
2004
Small-molecule inhibitors of protein–protein interactions: progressing towards the dream
M. Arkin
,
J. Wells
Nature Reviews Drug Discovery
2004
Corpus ID: 13879559
Protein–protein interactions have a key role in most biological processes, and offer attractive opportunities for therapeutic…
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