Skp2 Proteins

Known as: SKP2, p45, S-Phase Kinase-Associated Protein 2, p45 SKP2 
S-phase kinase-associated protein 2 (424 aa, ~48 kDa) is encoded by the human SKP2 gene. This protein is involved in the regulation of protein… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1996-2018
0102019962018

Papers overview

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2009
2009
Epigenetic silencing of secreted wingless-type (Wnt) antagonists through hypermethylation is associated with tobacco smoking and… (More)
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Highly Cited
2007
Highly Cited
2007
S-phase kinase-associated protein 2 (SKP2) is a component of the E3 ubiquitin ligase SKP1-Cul1-Fbox complex. Overexpression of… (More)
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Highly Cited
2007
Highly Cited
2007
Overexpression of CKS1B, a gene mapping within a minimally amplified region between 153 to 154 Mb of chromosome 1q21, is linked… (More)
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Highly Cited
2005
Highly Cited
2005
Cyclin-dependent kinase inhibitors (CKIs) and Notch receptor activation have been shown to influence adult stem cells and… (More)
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Highly Cited
2004
Highly Cited
2004
Cell-cycle transitions are driven by waves of ubiquitin-dependent degradation of key cell-cycle regulators. SCF (Skp1/Cullin/F… (More)
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2002
2002
We investigated DNA copy-number aberrations in 22 cell lines derived from small cell lung cancers (SCLCs) using comparative… (More)
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Highly Cited
1999
Highly Cited
1999
Degradation of the mammalian cyclin-dependent kinase (CDK) inhibitor p27 is required for the cellular transition from quiescence… (More)
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Highly Cited
1998
Highly Cited
1998
Genetic analysis in Arabidopsis has led to the identification of several genes that are required for auxin response. One of these… (More)
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Highly Cited
1998
Highly Cited
1998
Deregulation of cell proliferation is a hallmark of cancer. In many transformed cells, the cyclin A/CDK2 complex that contains S… (More)
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Highly Cited
1998
Highly Cited
1998
In normal and transformed cells, the F-box protein p45(SKP2) is required for S phase and forms stable complexes with p19(SKP1… (More)
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