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Skp2 Proteins

Known as: SKP2, p45, S-Phase Kinase-Associated Protein 2, p45 SKP2 
S-phase kinase-associated protein 2 (424 aa, ~48 kDa) is encoded by the human SKP2 gene. This protein is involved in the regulation of protein… Expand
National Institutes of Health

Papers overview

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Highly Cited
2016
Highly Cited
2016
Autophagy is a highly conserved self-digestion process, which is essential for maintaining homeostasis and viability in response… Expand
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Highly Cited
2012
Highly Cited
2012
The inhibitory receptor PD-1 blocks T cell proliferation by preventing cells from leaving the G1 phase of the cell cycle. PD-1… Expand
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Review
2008
Review
2008
The maintenance and preservation of distinct phases during the cell cycle is a highly complex and coordinated process. It is… Expand
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Highly Cited
2007
Highly Cited
2007
S-phase kinase-associated protein 2 (SKP2) is a component of the E3 ubiquitin ligase SKP1-Cul1-Fbox complex. Overexpression of… Expand
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Highly Cited
2007
Highly Cited
2007
Overexpression of CKS1B, a gene mapping within a minimally amplified region between 153 to 154 Mb of chromosome 1q21, is linked… Expand
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Highly Cited
2006
Highly Cited
2006
Androgen receptor (AR) plays a central role in prostate cancer, and most patients respond to androgen deprivation therapies, but… Expand
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Highly Cited
2001
Highly Cited
2001
The F-box protein Skp2 (S-phase kinase-associated protein 2) positively regulates the G1-S transition by controlling the… Expand
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Highly Cited
1999
Highly Cited
1999
Degradation of the mammalian cyclin-dependent kinase (CDK) inhibitor p27 is required for the cellular transition from quiescence… Expand
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Highly Cited
1998
Highly Cited
1998
Deregulation of cell proliferation is a hallmark of cancer. In many transformed cells, the cyclin A/CDK2 complex that contains S… Expand
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Highly Cited
1998
Highly Cited
1998
Genetic analysis in Arabidopsis has led to the identification of several genes that are required for auxin response. One of these… Expand
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