Signal Transduction Pathways
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The stimulation of Toll-like receptor 4 (TLR4) by lipopolysaccharide (LPS) induces the release of critical proinflammatory… Expand In their roles as major adhesion receptors, integrins signal across the plasma membrane in both directions. Recent structural and… Expand The c-Jun NH(2)-terminal kinase (JNK) is a member of an evolutionarily conserved sub-family of mitogen-activated protein (MAP… Expand The molecular details of mammalian stress-activated signal transduction pathways have only begun to be dissected. This, despite… Expand The p38 signalling transduction pathway, a Mitogen-activated protein (MAP) kinase pathway, plays an essential role in regulating… Expand PRL is an anterior pituitary hormone that, along with GH and PLs, forms a family of hormones that probably resulted from the… Expand Abstract Mitogen-activated protein (MAP) kinases are proline-directed serine/threonine kinases that are activated by dual… Expand Adhesive interactions play critical roles in directing the migration, proliferation, and differentiation of cells; aberrations in… Expand Mammalian mitogen-activated protein (MAP) kinases include extracellular signal-regulated protein kinase (ERK), c-Jun amino… Expand Treatment of cells with pro-inflammatory cytokines or ultraviolet radiation causes activation of the c-Jun NH2-terminal protein… Expand