Serpins

Known as: Serpin, Serpins [Chemical/Ingredient] 
A family of serine proteinase inhibitors which are similar in amino acid sequence and mechanism of inhibition, but differ in their specificity toward… (More)
National Institutes of Health

Papers overview

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Highly Cited
2014
Highly Cited
2014
Brain metastasis is an ominous complication of cancer, yet most cancer cells that infiltrate the brain die of unknown causes… (More)
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Review
2009
Review
2009
Point mutations cause members of the serine protease inhibitor (serpin) superfamily to undergo a novel conformational transition… (More)
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Highly Cited
2008
Highly Cited
2008
Repeating intermolecular protein association by means of β-sheet expansion is the mechanism underlying a multitude of diseases… (More)
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Highly Cited
2007
Highly Cited
2007
HDL lowers the risk for atherosclerotic cardiovascular disease by promoting cholesterol efflux from macrophage foam cells… (More)
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Review
2003
Review
2003
The superfamily of serine proteinase inhibitors (serpins) are involved in a number of fundamental biological processes such as… (More)
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Review
2003
Review
2003
Serpins are unique among the various types of active site proteinase inhibitors because they covalently trap their targets by… (More)
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Review
2001
Review
2001
Published, JBC Papers in Press, July 2, 2001, DOI 10.1074/jbc.R100016200 Gary A. Silverman, Phillip I. Bird, Robin W. Carrell… (More)
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Highly Cited
2000
Highly Cited
2000
The serpins have evolved to be the predominant family of serine-protease inhibitors in man. Their unique mechanism of inhibition… (More)
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Highly Cited
2000
Highly Cited
2000
We present a comprehensive alignment and phylogenetic analysis of the serpins, a superfamily of proteins with known members in… (More)
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Highly Cited
1997
Highly Cited
1997
Murine gammaherpesvirus 68 (gammaHV68) infects mice, thus providing a tractable small-animal model for analysis of the acute and… (More)
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