Serotonin

Known as: 5ht, 3-(2-Aminoethyl)-1H-indol-5-ol, 5-ht 
A biochemical messenger and regulator, synthesized from the essential amino acid L-TRYPTOPHAN. In humans it is found primarily in the central nervous… (More)
National Institutes of Health

Related topics

Related topics

48 relations

Narrower (27)

1-oxo-5-hydroxytryptamine111In-bis-5-hydroxytryptamide-diethylenetriamine-pentaacetate2-methyl-5-HT4,6-difluoroserotonin
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Broader (6)

AminesAutacoidsNeurotransmittersSerotonin Agonists
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In BloodNucleus Raphe MagnusProcess of secretionSerotonin Agents
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Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2017
Review
2017
Cannabis, Cannabinoids, and Sleep: a Review of the Literature.
PURPOSE OF REVIEW The current review aims to summarize the state of research on cannabis and sleep up to 2014 and to review in… (More)
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Review
2016
Review
2016
The role of monoamine oxidase A in aggression: Current translational developments and future challenges
Drawing upon the recent resurgence of biological criminology, several studies have highlighted a critical role for genetic… (More)
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Highly Cited
2003
Highly Cited
2003
Requirement of hippocampal neurogenesis for the behavioral effects of antidepressants.
Various chronic antidepressant treatments increase adult hippocampal neurogenesis, but the functional importance of this… (More)
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Highly Cited
2001
Highly Cited
2001
Amphetamine-type central nervous system stimulants release norepinephrine more potently than they release dopamine and serotonin.
A large body of evidence supports the hypothesis that mesolimbic dopamine (DA) mediates, in animal models, the reinforcing… (More)
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Highly Cited
1999
Highly Cited
1999
Role of serotonin in the paradoxical calming effect of psychostimulants on hyperactivity.
The mechanism by which psychostimulants act as calming agents in humans with attention-deficit hyperactivity disorder (ADHD) or… (More)
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Highly Cited
1998
Highly Cited
1998
Elevated anxiety and antidepressant-like responses in serotonin 5-HT1A receptor mutant mice.
The brain serotonin (5-hydroxytryptamine; 5-HT) system is a powerful modulator of emotional processes and a target of medications… (More)
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Highly Cited
1998
Highly Cited
1998
Serotonin receptor 1A knockout: an animal model of anxiety-related disorder.
To investigate the contribution of individual serotonin (5-hydroxytryptamine; 5-HT) receptors to mood control, we have used… (More)
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Highly Cited
1997
Highly Cited
1997
Differences between males and females in rates of serotonin synthesis in human brain.
Rates of serotonin synthesis were measured in the human brain using positron emission tomography. The sensitivity of the method… (More)
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Highly Cited
1996
Highly Cited
1996
Allelic variation of human serotonin transporter gene expression.
Mood, emotion, cognition, and motor functions as well as circadian and neuroendocrine rhythms, including food intake, sleep, and… (More)
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Highly Cited
1990
Highly Cited
1990
Serotonin function and the mechanism of antidepressant action. Reversal of antidepressant-induced remission by rapid depletion of plasma tryptophan.
Brain serotonin content is dependent on plasma levels of the essential amino acid tryptophan. We investigated the behavioral… (More)
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