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Serotonin

Known as: 5ht, 3-(2-Aminoethyl)-1H-indol-5-ol, 5-ht 
A biochemical messenger and regulator, synthesized from the essential amino acid L-TRYPTOPHAN. In humans it is found primarily in the central nervous… 
National Institutes of Health

Related topics

Related topics

47 relations

Narrower (24)

1-oxo-5-hydroxytryptamine111In-bis-5-hydroxytryptamide-diethylenetriamine-pentaacetate2-methyl-5-HT4,6-difluoroserotonin

Broader (6)

AminesAutacoidsNeurotransmittersSerotonin Agonists
In BloodNucleus Raphe MagnusProcess of secretionSerotonin Ag:PrThr:Pt:Tiss:Ord:Immune stain

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2003
Highly Cited
2003
Synthesis of Serotonin by a Second Tryptophan Hydroxylase Isoform
The neurotransmitter serotonin [5-hydroxytryptamine (5-HT)] is causally involved in multiple central nervous facets of mood… 
Review
2001
Review
2001
Spinal and supraspinal factors in human muscle fatigue.
Muscle fatigue is an exercise-induced reduction in maximal voluntary muscle force. It may arise not only because of peripheral… 
Highly Cited
1996
Highly Cited
1996
Allelic Variation of Human Serotonin Transporter Gene Expression
Abstract: Mood, emotion, cognition, and motor functions as well as circadian and neuroendocrine rhythms, including food intake… 
Review
1994
Review
1994
International Union of Pharmacology classification of receptors for 5-hydroxytryptamine (Serotonin).
It is evident that in the last decade or so, a vast amount of new information has become available concerning the various 5-HT… 
Review
1992
Review
1992
Structure and function of the brain serotonin system.
Highly Cited
1982
Highly Cited
1982
Lithium amplifies agonist-dependent phosphatidylinositol responses in brain and salivary glands.
1. The effect of Li+ on the agonist-dependent metabolism of [3H]inositol has been studied in rat brain, rat parotid and the… 
Highly Cited
1977
Highly Cited
1977
Contractile properties of small arterial resistance vessels in spontaneously hypertensive and normotensive rats.
The small arteries play an important functional role in establishing the increased peripheral resistance found in essential… 
Highly Cited
1971
Highly Cited
1971
Stereotaxic mapping of the monoamine pathways in the rat brain.
  • U. Ungerstedt
  • Acta physiologica Scandinavica. Supplementum
  • 1971
  • Corpus ID: 45492572
The ascending monoamine pathways in the rat brain are demonstrated by the pile up of fluorescent material occurring in the axons… 
Highly Cited
1971
Highly Cited
1971
Brain Serotonin Content: Physiological Dependence on Plasma Tryptophan Levels
Brain serotonin cocentrations at 1 p.m. were significantly elevated 1 hour after rats received a dose of L-tryptophan (12.5… 
Highly Cited
1966
Highly Cited
1966
p-Chlorophenylalanine: a specific depletor of brain serotonin.
  • B. Koe, A. Weissman
  • The Journal of pharmacology and experimental…
  • 1966
  • Corpus ID: 35484168
p -Chlorophenylalanine has been found to be a potent and selective depletor of brain serotonin (5HT) in mice, rats and dogs… 
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