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Serotonin

Known as: 5ht, 3-(2-Aminoethyl)-1H-indol-5-ol, 5-ht 
A biochemical messenger and regulator, synthesized from the essential amino acid L-TRYPTOPHAN. In humans it is found primarily in the central nervous… 
National Institutes of Health

Related topics

Related topics

47 relations

Narrower (24)

1-oxo-5-hydroxytryptamine111In-bis-5-hydroxytryptamide-diethylenetriamine-pentaacetate2-methyl-5-HT4,6-difluoroserotonin

Broader (6)

AminesAutacoidsNeurotransmittersSerotonin Agonists
In BloodNucleus Raphe MagnusProcess of secretionSerotonin Ag:PrThr:Pt:Tiss:Ord:Immune stain

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
1978
Highly Cited
1978
Inhibitors of neuronal monoamine uptake. 2. Selective inhibition of 5-hydroxytryptamine uptake by alpha-amino acid esters of phenethyl alcohols.
A series of alpha-amino acid esters of substituted phenethyl alcohols was prepared and tested as inhibitors of the neuronal… 
Highly Cited
1976
Highly Cited
1976
Sympathetic nerve endings in the pineal gland protect against acute stress-induced increase in N-acetyltransferase (EC 2.3.1.5.) activity.
Injection of the antidepressant desmyethylimipramine (DMI, 10 mg/kg) into intact rats or into rats in which the superior cervical… 
Highly Cited
1976
Highly Cited
1976
Pharmacologic Influences on Human Ovarian Contractions
Spontaneous motility in whole ovarian follicles, as well as in strips from the stroma and capsule of ovaries isolated from… 
Highly Cited
1974
Highly Cited
1974
Intraventricular injection of 5-hydroxytryptamine and alcohol consumption in rats.
Highly Cited
1967
Highly Cited
1967
A possible role played by central monoamine neurones in thermo-regulation.
The effect of a cold and warm environment on the activity of the central catecholamine (CA) and 5-hydroxytryptamine (5-HT… 
Highly Cited
1966
Highly Cited
1966
Effect of aggregating agents and their inhibitors on the mean platelet shape
The `swirling' seen when platelet-rich plasma is stirred is caused by the average asymmetry of the platelets and a technique for… 
Review
1965
Review
1965
Release of 5‐hydroxytryptamine from blood platelets *
  • M. Paasonen
  • The Journal of pharmacy and pharmacology
  • 1965
  • Corpus ID: 27451143
HE results of Rand & Reid (1951) originally pointed to the high T content of 5-hydroxytryptamine (~-HT) in blood platelets. Later… 
Highly Cited
1964
Highly Cited
1964
BRONCHOCONSTRICTOR ACTION AND ANTAGONISM OF A SLOW-REACTING SUBSTANCE FROM ANAPHYLAXIS OF GUINEA-PIG ISOLATED LUNG.
Slow-reacting substance produced in anaphylaxis (SRS-A) increased resistance of the lungs to inflation in the guinea-pig in vivo… 
Highly Cited
1960
Highly Cited
1960
5-HYDROXYINDOLES IN MENTAL DEFICIENCY
During a previous investigation in which a decreased production of 5-hydroxyindoles was demonstrated in phenylketonuric patients… 
Highly Cited
1958
Highly Cited
1958
Inhibition by various substances of oedema formation in the bind-paw of the rat induced by 5-hydroxytryptamine, histamine, dextran, egg-white and compound 48/80.
Of the substances studied for their inhibitory action of the oedema formation in the hind-paw of the rat, the most active was a…