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Sequest Scoring Engine

Known as: Sequest 
A proprietary scoring engine from Thermo Fisher Scientific that can match tandem mass spectra with peptide sequences.
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
MassWiz: a novel scoring algorithm with target-decoy based analysis pipeline for tandem mass spectrometry.
Mass spectrometry has made rapid advances in the recent past and has become the preferred method for proteomics. Although many… 
Highly Cited
2009
Highly Cited
2009
IDEAL-Q, an Automated Tool for Label-free Quantitation Analysis Using an Efficient Peptide Alignment Approach and Spectral Data Validation*
In this study, we present a fully automated tool, called IDEAL-Q, for label-free quantitation analysis. It accepts raw data in… 
2008
2008
SeMoP: a new computational strategy for the unrestricted search for modified peptides using LC-MS/MS data.
A novel computational approach, termed Search for Modified Peptides (SeMoP), for the unrestricted discovery and verification of… 
Review
2006
Review
2006
Verification of single-peptide protein identifications by the application of complementary database search algorithms.
Data produced from the MudPIT analysis of yeast (S. cerevisiae) and rice (O. sativa) were used to develop a technique to validate… 
Highly Cited
2006
Highly Cited
2006
Coupling the immobilized trypsin microreactor of monolithic capillary with muRPLC-MS/MS for shotgun proteome analysis.
A nanoliter trypsin-based monolithic microreactor coupled with muRPLC-MS/MS was reported for shotgun proteome analysis. The… 
Highly Cited
2005
Highly Cited
2005
Guidelines for the Routine Application of the Peptide Hits Technique
Review
2005
Review
2005
Protein Identification Using TurboSEQUEST
SEQUEST is the most widely used software tool for identifying proteins in complex mixtures. It is a mature, robust program that… 
Highly Cited
2004
Highly Cited
2004
Global Analysis of the Cortical Neuron Proteome *S
In this study, a multidimensional fractionation approach was combined with MS/MS to increase the capability of characterizing… 
Highly Cited
2003
Highly Cited
2003
Investigative proteomics: Identification of an unknown plant virus from infected plants using mass spectrometry
Highly Cited
2000
Highly Cited
2000
Characterization of cysteine residues and disulfide bonds in proteins by liquid chromatography/electrospray ionization tandem mass spectrometry.
Cysteine residues and disulfide bonds are important for protein structure and function. We have developed a simple and sensitive… 
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