Skip to search formSkip to main contentSkip to account menu

Sequest Scoring Engine

Known as: Sequest 
A proprietary scoring engine from Thermo Fisher Scientific that can match tandem mass spectra with peptide sequences.
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2010
Highly Cited
2010
Confident Phosphorylation Site Localization Using the Mascot Delta Score
Large scale phosphorylation analysis is more and more getting into focus of proteomic research. Although it is now possible to… 
Highly Cited
2009
Highly Cited
2009
IDEAL-Q, an Automated Tool for Label-free Quantitation Analysis Using an Efficient Peptide Alignment Approach and Spectral Data Validation*
In this study, we present a fully automated tool, called IDEAL-Q, for label-free quantitation analysis. It accepts raw data in… 
Highly Cited
2008
Highly Cited
2008
Statistical validation of peptide identifications in large-scale proteomics using the target-decoy database search strategy and flexible mixture modeling.
Reliable statistical validation of peptide and protein identifications is a top priority in large-scale mass spectrometry based… 
Review
2007
Review
2007
Comparative Evaluation of Tandem MS Search Algorithms Using a Target-Decoy Search Strategy*S
Peptide identification of tandem mass spectra by a variety of available search algorithms forms the foundation for much of modern… 
Highly Cited
2005
Highly Cited
2005
A comparison of immobilized pH gradient isoelectric focusing and strong‐cation‐exchange chromatography as a first dimension in shotgun proteomics
Recently, we have developed a high‐resolution two‐dimensional separation strategy for the analysis of complex peptide mixtures… 
Highly Cited
2003
Highly Cited
2003
GutenTag: high-throughput sequence tagging via an empirically derived fragmentation model.
Shotgun proteomics is a powerful tool for identifying the protein content of complex mixtures via liquid chromatography and… 
Highly Cited
2003
Highly Cited
2003
Mining a tandem mass spectrometry database to determine the trends and global factors influencing peptide fragmentation.
A database of 5500 unique peptide tandem mass spectra acquired in an ion trap mass spectrometer was assembled for peptides… 
Highly Cited
2003
Highly Cited
2003
MS2Assign, automated assignment and nomenclature of tandem mass spectra of chemically crosslinked peptides
Highly Cited
2001
Highly Cited
2001
Mass Spectrometric Characterization of Proteins Extracted from Jurkat T Cell Detergent-Resistant Membrane Domains
Plasma membranes of most cell types are thought to contain microdomains commonly referred to as lipid rafts, biochemically… 
Highly Cited
2001
Highly Cited
2001
In vivo MHC class II presentation of cytosolic proteins revealed by rapid automated tandem mass spectrometry and functional analyses
We report a strategy for high through‐put sequence analyses of large MHC class II‐bound peptide repertoires which combines… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)