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Selenoprotein P, human

Known as: SEPP1, SeP, Selenoprotein P 
Selenoprotein P (381 aa, ~43 kDa) is encoded by the human SEPP1 gene. This protein is involved in the modulation of selenium metabolism.
National Institutes of Health

Papers overview

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2015
2015
Patients with inflammatory bowel disease are at increased risk for colon cancer due to augmented oxidative stress. These patients… Expand
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Review
2015
Review
2015
Selenium is regulated in the body to maintain vital selenoproteins and to avoid toxicity. When selenium is limiting, cells… Expand
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Review
2013
Review
2013
The essential trace element selenium, as selenocysteine, is incorporated into antioxidant selenoproteins such as glutathione… Expand
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Highly Cited
2012
Highly Cited
2012
Background: Sepp1 transports selenium, but its complete role in selenium homeostasis is not known. Results: Deletion of Sepp1 in… Expand
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Highly Cited
2011
Highly Cited
2011
Oxidative stress and low-grade inflammation have been implicated in obesity and insulin resistance. As a selenium transporter… Expand
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Highly Cited
2010
Highly Cited
2010
BACKGROUND The intake of selenium needed for optimal health has not been established. Selenoproteins perform the functions of… Expand
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Review
2009
Review
2009
Selenoprotein P (Sepp1) is a secreted protein that is made up of 2 domains. The larger N-terminal domain contains 1… Expand
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Highly Cited
2008
Highly Cited
2008
Selenoprotein P (Sepp1) contains most of the selenium in blood plasma, and it is utilized by the kidney, brain, and testis as a… Expand
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Highly Cited
2007
Highly Cited
2007
Selenium is a micronutrient that is essential for the production of normal spermatozoa. The selenium-rich plasma protein… Expand
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Highly Cited
2007
Highly Cited
2007
Selenoprotein P (Sepp1) has two domains with respect to selenium content: the N-terminal, selenium-poor domain and the C-terminal… Expand
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