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Selenoprotein P, human

Known as: SEPP1, SeP, Selenoprotein P 
Selenoprotein P (381 aa, ~43 kDa) is encoded by the human SEPP1 gene. This protein is involved in the modulation of selenium metabolism.
National Institutes of Health

Related topics

Related topics

6 relations
Extracellular SpaceLigand BindingPlasmaSEPP1 gene

Broader (1)

Selenoprotein P

Papers overview

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Highly Cited
2017
Highly Cited
2017
Chronic Oxidative Stress, Mitochondrial Dysfunction, Nrf2 Activation and Inflammation in the Hippocampus Accompany Heightened Systemic Inflammation and Oxidative Stress in an Animal Model of Gulf War…
Memory and mood dysfunction are the key symptoms of Gulf war illness (GWI), a lingering multi-symptom ailment afflicting >200,000… 
Highly Cited
2015
Highly Cited
2015
Selenoprotein P influences colitis-induced tumorigenesis by mediating stemness and oxidative damage.
Patients with inflammatory bowel disease are at increased risk for colon cancer due to augmented oxidative stress. These patients… 
Highly Cited
2014
Highly Cited
2014
Effect of selenium on markers of risk of pre-eclampsia in UK pregnant women: a randomised, controlled pilot trial
Pre-eclampsia is a serious hypertensive condition of pregnancy associated with high maternal and fetal morbidity and mortality… 
Highly Cited
2014
Highly Cited
2014
Effects of Dietary Selenium Deficiency on mRNA Levels of Twenty-One Selenoprotein Genes in the Liver of Layer Chicken
Selenium (Se) is an essential trace element in many life forms due to its occurrence as selenocysteine (Sec) residue in… 
Highly Cited
2014
Highly Cited
2014
Transcriptional profile of genes involved in oxidative stress and antioxidant defense in PC12 cells following treatment with cerium oxide nanoparticles.
Highly Cited
2011
Highly Cited
2011
Reducing selenoprotein P expression suppresses adipocyte differentiation as a result of increased preadipocyte inflammation.
Oxidative stress and low-grade inflammation have been implicated in obesity and insulin resistance. As a selenium transporter… 
Highly Cited
2008
Highly Cited
2008
Neurodegeneration in Mice Resulting From Loss of Functional Selenoprotein P or Its Receptor Apolipoprotein E Receptor 2
Selenoprotein P (Sepp1) is involved in selenium homeostasis. Mice with a deletion of Sepp1, replacement of it by the shortened… 
Highly Cited
2006
Highly Cited
2006
Deletion of selenoprotein P upregulates urinary selenium excretion and depresses whole-body selenium content.
Highly Cited
2006
Highly Cited
2006
Altered hippocampus synaptic function in selenoprotein P deficient mice
Selenium is an essential micronutrient that function through selenoproteins. Selenium deficiency results in lower concentrations… 
Highly Cited
1979
Highly Cited
1979
PHOSPHODIESTERS IN MUSCULAR DYSTROPHIES *
Phosphorus nuclear magnetic resonance studies of various normal and dystrophic muscles have demonstrated differences in… 
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