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Selenoprotein P, human

Known as: SEPP1, SeP, Selenoprotein P 
Selenoprotein P (381 aa, ~43 kDa) is encoded by the human SEPP1 gene. This protein is involved in the modulation of selenium metabolism.
National Institutes of Health

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Related topics

6 relations
Extracellular SpaceLigand BindingPlasmaSEPP1 gene

Broader (1)

Selenoprotein P

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Identification of SEPP1 polymorphisms is not a genetic risk factor for preeclampsia in Chinese Han women
Background: SEPP1 encodes selenoprotein P, which involved in oxidative stress and plays an important role in the development of… 
2017
2017
IS THERE A RELATIONSHIP BETWEEN SELENOPROTEIN P1 (SEPP1) GENE POLYMORPHISM AND GESTATIONAL DIABETES MELLITUS IN TURKISH WOMEN
Objective : Diabetes Mellitus (DM) is a complex disease caused by a combination of genetic and environmental factors… 
2014
2014
Isoform-specific Binding of Selenoprotein P to the β-Propeller Domain of Apolipoprotein E Receptor 2 Mediates Selenium Supply*
Background: ApoER2 facilitates uptake of Sepp1, but the binding mechanism has not been elucidated. Results: The two longest… 
Highly Cited
2014
Highly Cited
2014
Selenoprotein P as a diabetes-associated hepatokine that impairs angiogenesis by inducing VEGF resistance in vascular endothelial cells
Aims/hypothesisImpaired angiogenesis induced by vascular endothelial growth factor (VEGF) resistance is a hallmark of vascular… 
2014
2014
Selenoprotein P Is the Major Selenium Transport Protein in Mouse Milk
Selenium is transferred from the mouse dam to its neonate via milk. Milk contains selenium in selenoprotein form as selenoprotein… 
2014
2014
Intestinal selenoprotein P in epithelial cells and in plasma cells.
2013
2013
Polymorphisms in genes encoding antioxidant enzymes (SOD2, CAT, GPx, TXNRD, SEPP1, SEP15 and SELS) and risk of chronic kidney disease in Japanese - cross-sectional data from the J-MICC study
Chronic kidney disease (CKD) is well known as a strong risk factor for both of end-stage renal disease and cardiovascular disease… 
Highly Cited
2012
Highly Cited
2012
Absence of selenoprotein P but not selenocysteine lyase results in severe neurological dysfunction
Dietary selenium restriction in mammals causes bodily selenium to be preferentially retained in the brain relative to other… 
2010
2010
Selenoprotein P gene r25191g/a polymorphism and quantification of selenoprotein P mRNA level in patients with Kashin-Beck disease.
Kashin-Beck disease (KBD) is an endemic and deformable osteoarthrosis. Epidemiological study has revealed that lower Se level is… 
1991
1991
Alteration of SEP topography in Huntington's patients and their relatives at risk.
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