Segmentation Clock Pathway

Known as: Segmentation Clock 
In most animal species, the anteroposterior body axis is generated by the formation of repeated structures called segments. In vertebrate… (More)
National Institutes of Health

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Review
2012
Review
2012
The segmentation clock is an oscillating genetic network thought to govern the rhythmic and sequential subdivision of the… (More)
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Highly Cited
2007
Highly Cited
2007
The "segmentation clock" is thought to coordinate sequential segmentation of the body axis in vertebrate embryos. This clock… (More)
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Highly Cited
2006
Highly Cited
2006
The segmental pattern of the spine is established early in development, when the vertebral precursors, the somites, are… (More)
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Highly Cited
2006
Highly Cited
2006
Periodic somite segmentation in vertebrate embryos is controlled by the ‘segmentation clock’, which consists of numerous cellular… (More)
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Highly Cited
2004
Highly Cited
2004
During somitogenesis, a pair of somites buds off from the presomitic mesoderm every 2 hours in mouse embryos, suggesting that… (More)
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Review
2003
Review
2003
In most animal species, the anteroposterior body axis is generated by the formation of repeated structures called segments. In… (More)
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Is this relevant?
Highly Cited
2003
Highly Cited
2003
The vertebral column derives from somites generated by segmentation of presomitic mesoderm (PSM). Somitogenesis involves a… (More)
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Highly Cited
2003
Highly Cited
2003
The segmented aspect of the vertebrate body plan first arises through the sequential formation of somites. The periodicity of… (More)
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Highly Cited
2001
Highly Cited
2001
During development, Hox gene transcription is activated in presomitic mesoderm with a time sequence that follows the order of the… (More)
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Highly Cited
2000
Highly Cited
2000
In vertebrates with mutations in the Notch cell–cell communication pathway, segmentation fails: the boundaries demarcating… (More)
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