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DKK1 wt Allele
Known as:
UNQ492/PRO1008
, DKK-1
, Dickkopf Homolog 1 (Xenopus laevis) wt Allele
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Human DKK1 wild-type allele is located in the vicinity of 10q11.2 and is approximately 4 kb in length. This allele, which encodes dickkopf-related…
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National Institutes of Health
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Related topics
Related topics
11 relations
10q11.2
Beta-Catenin Accumulation Pathway
Dickkopf-Related Protein 1
Intercellular Communication Process
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Broader (1)
DKK1 gene
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2016
Highly Cited
2016
Berberine promotes bone marrow-derived mesenchymal stem cells osteogenic differentiation via canonical Wnt/β-catenin signaling pathway.
K. Tao
,
Deming Xiao
,
Jian Weng
,
Ao Xiong
,
Bin Kang
,
H. Zeng
Toxicology Letters
2016
Corpus ID: 29210522
Highly Cited
2014
Highly Cited
2014
Effects of Interleukin-17A on Osteogenic Differentiation of Isolated Human Mesenchymal Stem Cells
B. Osta
,
F. Lavocat
,
A. Eljaafari
,
P. Miossec
Frontiers in Immunology
2014
Corpus ID: 15427510
Objectives: Rheumatoid arthritis (RA) is characterized by defective bone repair and excessive destruction and ankylosing…
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Highly Cited
2012
Highly Cited
2012
p38 MAPK in myeloma cells regulates osteoclast and osteoblast activity and induces bone destruction.
Jin He
,
Zhiqiang Liu
,
+12 authors
Jing Yang
Cancer Research
2012
Corpus ID: 23745667
p38 mitogen-activated protein kinase (MAPK), which is constitutively activated in human myeloma, has been implicated in bone…
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Highly Cited
2011
Highly Cited
2011
The effects of shockwave on systemic concentrations of nitric oxide level, angiogenesis and osteogenesis factors in hip necrosis
Ching‐Jen Wang
,
Ya-Ju Yang
,
Chung-Cheng Huang
Rheumatology International
2011
Corpus ID: 22546609
This study investigated the effects of shockwave on systemic concentrations of nitric oxide (NO) level, angiogenic and osteogenic…
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Highly Cited
2010
Highly Cited
2010
Anticancer effects of flavonoid derivatives isolated from Millettia reticulata Benth in SK-Hep-1 human hepatocellular carcinoma cells.
S. Fang
,
Chin-Lin Hsu
,
Hsin-Tang Lin
,
G. Yen
Journal of Agricultural and Food Chemistry
2010
Corpus ID: 42888473
Millettia reticulata Benth is cultivated in Asian countries. M. reticulata Benth has multiple biological functions and is one of…
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Highly Cited
2008
Highly Cited
2008
Serum concentrations of DKK‐1 correlate with the extent of bone disease in patients with multiple myeloma
M. Kaiser
,
M. Mieth
,
+10 authors
U. Heider
European Journal of Haematology
2008
Corpus ID: 24585304
Objectives: Lytic bone disease is a hallmark of multiple myeloma (MM) and is caused by osteoclast activation and osteoblast…
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Highly Cited
2008
Highly Cited
2008
Prostate cancer induces bone metastasis through Wnt-induced bone morphogenetic protein-dependent and independent mechanisms.
Jinlu Dai
,
C. Hall
,
J. Escara-Wilke
,
A. Mizokami
,
Jill M. Keller
,
E. Keller
Cancer Research
2008
Corpus ID: 6159892
Prostate cancer (PCa) is frequently accompanied by osteosclerotic (i.e., excessive bone production) bone metastases. Although…
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Highly Cited
2008
Highly Cited
2008
Osteoclasts Are Active in Bone Forming Metastases of Prostate Cancer Patients
I. Roato
,
P. D’Amelio
,
+8 authors
R. Ferracini
PLoS ONE
2008
Corpus ID: 9977236
Background Bone forming metastases are a common and disabling consequence of prostate cancer (CaP). The potential role of…
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Highly Cited
2008
Highly Cited
2008
SK (KCa2) channels do not control somatic excitability in CA1 pyramidal neurons but can be activated by dendritic excitatory synapses and regulate their impact.
Ning Gu
,
Hua Hu
,
K. Vervaeke
,
J. Storm
Journal of Neurophysiology
2008
Corpus ID: 10956479
Calcium-activated K(+) channels of the K(Ca)2 type (SK channels) are prominently expressed in the mammalian brain, including…
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Highly Cited
2007
Highly Cited
2007
A potential role for Dkk-1 in the pathogenesis of osteosarcoma predicts novel diagnostic and treatment strategies
N. Lee
,
A. Smolarz
,
+7 authors
C. Gregory
British Journal of Cancer
2007
Corpus ID: 18863524
Canonical Wnt signalling is an osteoinductive signal that promotes bone repair through acceleration of osteogenic differentiation…
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