DKK1 gene

Known as: DICKKOPF, XENOPUS, HOMOLOG OF, 1, DKK1, DKK-1 
This gene is involved in intercellular communication.
National Institutes of Health

Topic mentions per year

Topic mentions per year

2000-2018
020406020002018

Papers overview

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Highly Cited
2010
Highly Cited
2010
OBJECTIVE To study whether Dickkopf (DKK)-1, an inhibitor of wingless (Wnt) signalling, is involved in the fusion of sacroiliac… (More)
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Highly Cited
2008
Highly Cited
2008
DKK1 is a secreted protein that antagonizes Wnt signaling and plays essential roles in vertebrate embryogenesis including head… (More)
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Highly Cited
2007
Highly Cited
2007
Activation of Wnt signaling has been implicated in tumorigenesis, and epigenetic silencing of Wnt antagonist genes has been… (More)
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Highly Cited
2007
Highly Cited
2007
R-spondin proteins are newly identified secreted molecules that activate beta-catenin signaling. However, the mechanism of R… (More)
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Highly Cited
2006
Highly Cited
2006
UNLABELLED Wnt/beta-catenin signaling has been proven to play a central role in bone biology. Unexpectedly, the Wnt antagonist… (More)
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Highly Cited
2006
Highly Cited
2006
Mutations affecting the activity of the Wnt co-receptors LRP5 and LRP6 that cause alterations in skeletal biology confirmed the… (More)
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Highly Cited
2005
Highly Cited
2005
beta-catenin is the major effector of the canonical Wnt signaling pathway. Mutations in components of the pathway that stabilize… (More)
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Highly Cited
2005
Highly Cited
2005
OBJECTIVE Various preparative protocols have been proposed for the acquisition and cultivation of mesenchymal stem cells (MSC… (More)
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Highly Cited
2004
Highly Cited
2004
Wnt signaling plays an important role in embryonic development and tumorigenesis. These biological effects are exerted by… (More)
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Highly Cited
2004
Highly Cited
2004
Autocrine Wnt signaling in the mouse mammary tumor virus model was the first identified mechanism of canonical pathway activation… (More)
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