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Scrapie

Known as: Rida, Scrapie [Disease/Finding] 
A fatal disease of the nervous system in sheep and goats, characterized by pruritus, debility, and locomotor incoordination. It is caused by… 
National Institutes of Health

Related topics

Related topics

10 relations
In BloodMicrobiologicalPrPSc ProteinsPrion Diseases

Broader (1)

Spongiform encephalopathy

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2007
Highly Cited
2007
Role of galectin-3 in prion infections of the CNS.
Highly Cited
2006
Highly Cited
2006
Polymorphism and ultrastructural organization of prion protein amyloid fibrils: an insight from high resolution atomic force microscopy.
Highly Cited
2002
Highly Cited
2002
Subclinical scrapie infection in a resistant species: persistence, replication, and adaptation of infectivity during four passages.
Cross-species infection with transmissible spongiform encephalopathy agents may lead to subclinical infection and to adaptation… 
Highly Cited
1996
Highly Cited
1996
Strain specific and common pathogenic events in murine models of scrapie and bovine spongiform encephalopathy.
The development of transmissible spongiform encephalopathies in experimental models depends on two major factors: the… 
Highly Cited
1993
Highly Cited
1993
Scrapie prions alter receptor‐mediated calcium responses in cultured cells
The molecular basis of neurologic dysfunction in prion diseases is unknown. Spongiform degeneration of neurons is the most… 
Highly Cited
1986
Highly Cited
1986
Detection of scrapie-associated fibril (SAF) proteins using anti-SAF antibody in non-purified tissue preparations.
Antisera raised to scrapie-associated fibril (SAF) proteins were used to detect scrapie-specific polypeptides in three different… 
Highly Cited
1985
Highly Cited
1985
Specific proteins associated with Creutzfeldt-Jakob disease and scrapie share antigenic and carbohydrate determinants.
Small amounts of brain tissue (2 g) infected with Creutzfeldt-Jakob disease (CJD) can be fractionated by using a simple 1-day… 
Highly Cited
1984
Highly Cited
1984
Preclinical changes in weight of scrapie-infected mice as a function of scrapie agent-mouse strain combination.
Several inbred strains of mice were injected with different scrapie agents and their total body weight was monitored throughout… 
Review
1984
Review
1984
Prions: novel infectious pathogens.
Highly Cited
1978
Highly Cited
1978
The scrapie agent: evidence against its dependence for replication on intrinsic nucleic acid.
Exposure of the scrapie agent to u.v. light at various wavelengths has shown that light of 237 nm is 4 to 5 times as effective in… 
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