Scrapie

Known as: Rida, Scrapie [Disease/Finding] 
A fatal disease of the nervous system in sheep and goats, characterized by pruritus, debility, and locomotor incoordination. It is caused by… (More)

Topic mentions per year

Topic mentions per year

1945-2018
0204019452017

Papers overview

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Highly Cited
2005
Highly Cited
2005
Prions are unconventional infectious agents responsible for transmissible spongiform encephalopathy (TSE) diseases. They are… (More)
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Highly Cited
2005
Highly Cited
2005
Scrapie in small ruminants belongs to transmissible spongiform encephalopathies (TSEs), or prion diseases, a family of fatal… (More)
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Highly Cited
2001
Highly Cited
2001
Exposure of susceptible neuroblastoma N2a cells to mouse scrapie prions leads to infection, as evidenced by the continued… (More)
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Highly Cited
2000
Highly Cited
2000
Ovine scrapie is a member of the transmissible spongiform encephalopathies (TSEs), a heterogeneous family of fatal neurologic… (More)
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Highly Cited
1995
Highly Cited
1995
Scrapie is a fatal neurodegenerative disease of sheep that belongs to the group of prion diseases found in humans and animals… (More)
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Highly Cited
1994
Highly Cited
1994
Man and sheep are the two species in which spongiform encephalopathies occur naturally, and in which there are recognized genetic… (More)
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Highly Cited
1993
Highly Cited
1993
S.B. Prusiner proposed that the infectious agent of scraple, the prion, is PrPSc, a modified form of the normal host protein PrPC… (More)
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Highly Cited
1986
Highly Cited
1986
PrP 27-30 is the major protein in purified preparations of scrapie agent. An almost complete PrP cDNA was used to select PrP… (More)
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Highly Cited
1986
Highly Cited
1986
Scrapie is a slow degenerative encephalopathy of animals caused by unusual infectious particles termed prions. A cDNA encoding… (More)
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Highly Cited
1983
Highly Cited
1983
A large scale purification protocol employing zonal rotor centrifugation has been developed for scrapie prions. The extensively… (More)
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