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Scrapie

Known as: Rida, Scrapie [Disease/Finding] 
A fatal disease of the nervous system in sheep and goats, characterized by pruritus, debility, and locomotor incoordination. It is caused by… 
National Institutes of Health

Related topics

Related topics

10 relations
In BloodMicrobiologicalPrPSc ProteinsPrion Diseases

Broader (1)

Spongiform encephalopathy

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2006
Highly Cited
2006
Polymorphism and ultrastructural organization of prion protein amyloid fibrils: an insight from high resolution atomic force microscopy.
Highly Cited
2004
Highly Cited
2004
Antigenic characterization of an abnormal isoform of prion protein using a new diverse panel of monoclonal antibodies.
Highly Cited
2003
Highly Cited
2003
Copper binding to PrPC may inhibit prion disease propagation
Highly Cited
2003
Highly Cited
2003
Destabilizing interactions among [PSI(+)] and [PIN(+)] yeast prion variants.
The yeast Sup35 and Rnq1 proteins can exist in either the noninfectious soluble forms, [psi-] or [pin-], respectively, or the… 
Review
2001
Review
2001
Three-dimensional structures of prion proteins.
Highly Cited
2001
Highly Cited
2001
PEGylated polycyanoacrylate nanoparticles as vector for drug delivery in prion diseases
Highly Cited
1987
Highly Cited
1987
Purified prion proteins and scrapie infectivity copartition into liposomes.
Considerable evidence indicates that the scrapie prion protein (PrP 27-30) is required for infectivity. Aggregates of PrP 27-30… 
Highly Cited
1986
Highly Cited
1986
Monoclonal antibodies to the cellular and scrapie prion proteins.
Scrapie is a degenerative neurological disease of sheep and goats that has been experimentally transmitted to rodents. The… 
Highly Cited
1984
Highly Cited
1984
Molecular characteristics of the major scrapie prion protein.
A major protein was identified that purifies with the scrapie agent extracted from infected hamster brains. The protein… 
Highly Cited
1984
Highly Cited
1984
A rapid and efficient method to enrich SAF-protein from scrapie brains of hamsters
Scrapie hamster brains contain at least 5–10 μg of scrapie-associated fibrils (SAF) per brain as estimated by the amount of its… 
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