PrPSc Proteins

Known as: PrPSc Proteins [Chemical/Ingredient], Sp 33-35, PrP res 
Abnormal isoform of PRION PROTEINS resulting from a posttranslational modification of the cellular prion protein (PRPC PROTEINS). PrPSc are disease… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1985-2016
051019852016

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2012
2012
The molecular masses of the PrPres moieties from the 2 cows were also clearly distinct from those from controls with Land H-BSE… (More)
Is this relevant?
Highly Cited
2000
Highly Cited
2000
The transmissible spongiform encephalopathies (TSEs) are fatal, neurodegenerative diseases for which no effective treatments are… (More)
  • figure 1
  • table 1
  • table 2
  • figure 2
  • figure 3
Is this relevant?
Highly Cited
1999
Highly Cited
1999
The mechanism of protein-only prion replication is controversial. A detailed mathematical model of prion replication by nucleated… (More)
  • table 1
  • figure 2
  • table 2
  • table 3
  • figure 4
Is this relevant?
Highly Cited
1998
Highly Cited
1998
Strain diversity in the transmissible spongiform encephalopathies (TSEs) has been proposed to be determined by variations in the… (More)
Is this relevant?
Highly Cited
1998
Highly Cited
1998
The clinicopathological phenotype of the Gerstmann-Sträussler-Scheinker disease (GSS) variant linked to the codon 102 mutation in… (More)
Is this relevant?
Highly Cited
1997
Highly Cited
1997
Bovine spongiform encephalopathy (BSE) has become a public health issue because a recently evolved BSE agent has infected people… (More)
  • figure 1
  • figure 2
  • figure 3
Is this relevant?
Highly Cited
1994
Highly Cited
1994
A conformational conversion of the normal, protease- sensitive prion protein (PrP-sen or PrP(C)) to a protease-resistant form… (More)
Is this relevant?
Highly Cited
1993
Highly Cited
1993
The accumulation of an abnormal, protease-resistant form of the protein PrP (PrP-res) in hosts with scrapie and related… (More)
Is this relevant?
Highly Cited
1991
Highly Cited
1991
A protease-resistant form of the protein PrP (PrP-res) accumulates in tissues of mammals infected with scrapie, Creutzfeldt-Jakob… (More)
Is this relevant?
Highly Cited
1991
Highly Cited
1991
Scrapie and related transmissible spongiform encephalopathies result in the accumulation of a protease-resistant form of an… (More)
Is this relevant?