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STK11 gene

Known as: serine/threonine kinase 11, LKB1, Serine/Threonine Kinase 11 Gene 
This gene plays a role in cell cycle regulation. It is also putatively involved in glucose production.
National Institutes of Health

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Related topics

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ApoptosisBreast CarcinomaGastrointestinal NeoplasmsLKB1 Gene Inactivation

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STK11 wt Allele

Papers overview

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2016
2016
Genetic Screening and Analysis of LKB1 Gene in Chinese Patients with Peutz-Jeghers Syndrome
Background Peutz-Jeghers syndrome (PJS) is an autosomal dominant genetic disease. It severely decreases patient quality of life… 
2014
2014
Synergistic effects of eukaryotic coexpression plasmid carrying LKB1 and FUS1 genes on lung cancer in vitro and in vivo
PurposeLKB1 and FUS1 are two kinds of new tumor suppressor genes as well as early-stage genes in lung cancer. Recent studies… 
2014
2014
A pharmacogenetic association between a variation in calpain 10 (CAPN10) gene and the response to metformin treatment in patients with type 2 diabetes
The aim of the present study was to investigate possible associations of the single-nucleotide variants in six genes encoding the… 
2013
2013
LKB1 Mediates the Development of Conventional and Innate T Cells via AMP-Dependent Kinase Autonomous Pathways
The present study has examined the role of the serine/threonine kinase LKB1 in the survival and differentiation of CD4/8 double… 
2012
2012
LKB1 controls the pluripotent state of human embryonic stem cells.
Human embryonic stem cells maintained on human amniotic epithelial cells (hESCs(hAEC)) are better preserved in an… 
2010
2010
Evaluation of the contribution of the three breast cancer susceptibility genes CHEK2, STK11, and PALB2 in non-BRCA1/2 French Canadian families with high risk of breast cancer.
Inactivating mutations of the CHEK2 and STK11 genes are responsible for Li-Fraumeni and Peutz-Jeghers syndrome, respectively… 
2009
2009
LKB 1 is essential for the proliferation of T-cell progenitors and mature peripheral T cells
The serine/threonine kinase LKB1 has a conserved role in Drosophila and nematodes to co-ordinate cell metabolism. During T… 
2009
2009
LKB1 gene alterations in surgically resectable adenocarcinoma of the lung
PurposeGermline mutations of LKB1 (also known as SKT11; locus 19p13.3) cause the occurrence of autosomal dominant Peutz-Jeghers… 
2004
2004
Histotopochemische Untersuchungen am Reizleitungssystem des Hundeherzens
SummaryThe cardiac conduction system (sinus node, atrioventricular node and atrioventricular bundle) of the dog is characterized… 
2004
2004
Immunohistochemical study of blood group activities in the alimentary canal in normal and pathologic conditions with reference to the nature of epithelial mucopolysaccharides
SummaryABO(H)- and Lewis-activities in the human alimentary canal were investigated by the avidin-biotin-peroxidase complex… 
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