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STK11 gene

Known as: serine/threonine kinase 11, LKB1, Serine/Threonine Kinase 11 Gene 
This gene plays a role in cell cycle regulation. It is also putatively involved in glucose production.
National Institutes of Health

Related topics

Related topics

14 relations
ApoptosisBreast CarcinomaGastrointestinal NeoplasmsLKB1 Gene Inactivation

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STK11 wt Allele

Papers overview

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2014
2014
Synergistic effects of eukaryotic coexpression plasmid carrying LKB1 and FUS1 genes on lung cancer in vitro and in vivo
PurposeLKB1 and FUS1 are two kinds of new tumor suppressor genes as well as early-stage genes in lung cancer. Recent studies… 
2013
2013
LKB1 Mediates the Development of Conventional and Innate T Cells via AMP-Dependent Kinase Autonomous Pathways
The present study has examined the role of the serine/threonine kinase LKB1 in the survival and differentiation of CD4/8 double… 
2013
2013
Crystallization and preliminary crystallographic analysis of the chimeric protein LKB1-14-3-3ζ.
LKB1, a tumour suppressor, plays key roles in cell polarity, cell growth and energy metabolism. 14-3-3 proteins bind to LKB1 and… 
2010
2010
Immunohistological evidence for Wnt-signaling activation in Peutz-Jeghers polyposis
ObjectiveMolecular pathogenesis of gastrointestinal polyposis in Peutz-Jegher’s syndrome (PJS) has been linked to the loss-of… 
2009
2009
LKB1 gene alterations in surgically resectable adenocarcinoma of the lung
PurposeGermline mutations of LKB1 (also known as SKT11; locus 19p13.3) cause the occurrence of autosomal dominant Peutz-Jeghers… 
2008
2008
[Effect of transfection of LKB1 on biological behavior of human lung adenocarcinoma cells].
AIM To determine the effects of exogenous LKB1 gene on biological behavior of lung carcinoma cells. METHODS Nest PCR was used… 
2007
2007
High-level expression of functional tumor suppressor LKB1 in Escherichia coli.
The human LKB1 tumor suppressor has been implicated as an important regulator of many cellular processes and signaling pathways… 
2004
2004
Histotopochemische Untersuchungen am Reizleitungssystem des Hundeherzens
SummaryThe cardiac conduction system (sinus node, atrioventricular node and atrioventricular bundle) of the dog is characterized… 
2004
2004
Immunohistochemical study of blood group activities in the alimentary canal in normal and pathologic conditions with reference to the nature of epithelial mucopolysaccharides
SummaryABO(H)- and Lewis-activities in the human alimentary canal were investigated by the avidin-biotin-peroxidase complex… 
1999
1999
[STK11 gene mutation in Chinese with PJS].
OBJECTIVES To understand the mutation characteristic of STK11 gene in Chinese with Peutz-Jeghers syndrome and establish the gene… 
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