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STK11 wt Allele

Known as: Serine/Threonine Kinase 11 wt Allele, Serine/Threonine Kinase 11 (Peutz-Jeghers Syndrome) Gene, LKB1 
Human STK11 wild-type allele is located in the vicinity of 19p13.3 and is approximately 23 kb in length. This allele, which encodes serine/threonine… Expand
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
Human Papilloma Virus (HPV) is the etiologic agent for cervical cancer. Yet, infection with HPV is not sufficient to cause… Expand
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Highly Cited
2009
Highly Cited
2009
Purpose: The phosphatidylinositol 3-kinase (PI3K) pathway can be activated by alterations affecting several pathway components… Expand
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Highly Cited
2008
Highly Cited
2008
The LKB1 tumour suppressor phosphorylates and activates AMPK (AMP-activated protein kinase) when cellular energy levels are low… Expand
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Highly Cited
2007
Highly Cited
2007
Germline mutation in serine/threonine kinase 11 (STK11, also called LKB1) results in Peutz–Jeghers syndrome, characterized by… Expand
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Highly Cited
2005
Highly Cited
2005
Recent studies indicate that the LKB1 tumour suppressor protein kinase is the major 'upstream' activator of the energy sensor AMP… Expand
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Highly Cited
2005
Highly Cited
2005
Germline mutations of the LKB1 gene are responsible for the cancer-prone Peutz-Jeghers syndrome (PJS). LKB1 encodes a serine… Expand
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Highly Cited
2002
Highly Cited
2002
Germline mutations of the LKB1 tumor suppressor gene lead to Peutz-Jeghers syndrome (PJS), with a predisposition to cancer. LKB1… Expand
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Highly Cited
2000
Highly Cited
2000
Germ-line mutations of the LKB1 gene cause Peutz-Jeghers syndrome (PJS) characterized by mucocutaneous pigmentation… Expand
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Highly Cited
1999
Highly Cited
1999
Germ-line mutations of LKB1 (STK11) lead to Peutz-Jeghers syndrome characterized by gastrointestinal polyps and cancer of… Expand
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Highly Cited
1998
Highly Cited
1998
Peutz-Jeghers syndrome (PJS) is an autosomal dominant disease characterized by mucocutaneous pigmentation and hamartomatous… Expand
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