STK11 wt Allele

Known as: Serine/Threonine Kinase 11 wt Allele, Serine/Threonine Kinase 11 (Peutz-Jeghers Syndrome) Gene, LKB1 
Human STK11 wild-type allele is located in the vicinity of 19p13.3 and is approximately 23 kb in length. This allele, which encodes serine/threonine… (More)
National Institutes of Health

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Highly Cited
2011
Highly Cited
2011
Hypothesis-generating epidemiological research has suggested that cancer burden is reduced in diabetics treated with metformin… (More)
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Highly Cited
2010
Highly Cited
2010
BACKGROUND & AIMS Patients carrying germline mutations of LKB1 have an increased risk of pancreatic cancer; however, it is… (More)
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Highly Cited
2009
Highly Cited
2009
PURPOSE The phosphatidylinositol 3-kinase (PI3K) pathway can be activated by alterations affecting several pathway components… (More)
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Highly Cited
2009
Highly Cited
2009
Human Papilloma Virus (HPV) is the etiologic agent for cervical cancer. Yet, infection with HPV is not sufficient to cause… (More)
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Highly Cited
2007
Highly Cited
2007
Germline mutation in serine/threonine kinase 11 (STK11, also called LKB1) results in Peutz–Jeghers syndrome, characterized by… (More)
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Highly Cited
2002
Highly Cited
2002
Germline mutations of the LKB1 tumor suppressor gene lead to Peutz-Jeghers syndrome (PJS), with a predisposition to cancer. LKB1… (More)
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Highly Cited
2000
Highly Cited
2000
Germ-line mutations of the LKB1 gene cause Peutz-Jeghers syndrome (PJS) characterized by mucocutaneous pigmentation… (More)
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Highly Cited
1999
Highly Cited
1999
Germline mutations in LKB1 have been reported to underlie familial Peutz-Jeghers syndrome (PJS) with intestinal hamartomatous… (More)
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1999
1999
The protein kinase gene LKB1 has recently been identified as the gene mutated in the Peutz-Jeghers cancer predisposition syndrome… (More)
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Highly Cited
1998
Highly Cited
1998
Germ-line mutations in a serine/threonine kinase gene, LKB1, were recently shown to underlie Peutz-Jeghers syndrome (PJS), a… (More)
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