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STAT protein

Known as: STAT, Signal Transducer and Activator of Transcription 
A family of cytoplasmic proteins that are activated by phosphorylation in response to a large number of cytokines, growth factors, and hormones. They… 
National Institutes of Health

Related topics

Related topics

12 relations
STAT family geneSTAT1 protein, humanSTAT2 Transcription FactorSTAT4 protein

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2009
Review
2009
The T helper 17–regulatory T cell axis in transplant rejection and tolerance
Purpose of reviewRegulatory T cells (Tregs) are potential therapeutic tools in averting transplant rejection and promoting… 
Highly Cited
2007
Highly Cited
2007
Cross Talk between Notch and Growth Factor/Cytokine Signaling Pathways in Neural Stem Cells
ABSTRACT Precise control of proliferation and differentiation of multipotent neural stem cells (NSCs) is crucial for proper… 
Highly Cited
2005
Highly Cited
2005
Suppression of Stat3 promotes neurogenesis in cultured neural stem cells
To investigate the effects of signal transducer and activator of transcription 3 (Stat3) on neural stem cell fate, stem cells… 
Highly Cited
2004
Highly Cited
2004
A high-throughput fluorescence polarization assay for signal transducer and activator of transcription 3.
Highly Cited
2004
Highly Cited
2004
Acute allergen-induced airway remodeling in atopic asthma.
Studies in animals and in human atopic skin suggest that allergen challenge may activate acute tissue remodeling changes via… 
Highly Cited
2003
Highly Cited
2003
Activation of signal transducer and activator of transcription 3 by oncogenic RET/PTC (rearranged in transformation/papillary thyroid carcinoma) tyrosine kinase: roles in specific gene regulation and…
Thyroid papillary carcinomas are characterized by RET/PTC (rearranged in transformation/papillary thyroid carcinoma… 
Highly Cited
2000
Highly Cited
2000
Interleukin-6-induced STAT3 transactivation and Ser727 phosphorylation involves Vav, Rac-1 and the kinase SEK-1/MKK-4 as signal transduction components.
In the present study, signal transducer and activator of transcription 3 (STAT3) Ser(727) phosphorylation and transactivation was… 
Highly Cited
2000
Highly Cited
2000
Androgen and estrogen receptors in splenic T lymphocytes: effects of flutamide and trauma-hemorrhage.
The endogenous sex steroids, testosterone and beta-estradiol, play a major role in inflammatory processes. They regulate several… 
Highly Cited
2000
Highly Cited
2000
The role of CD154-CD40 versus CD28-B7 costimulatory pathways in regulating allogeneic Th1 and Th2 responses in vivo.
We used signal transducer and activator of transcription 4 (STAT4) and STAT6 gene knockout (-/-) mice as recipients of fully… 
Highly Cited
1998
Highly Cited
1998
Stat Proteins Control Lymphocyte Proliferation by Regulating p27Kip1 Expression
ABSTRACT The proliferation of lymphocytes in response to cytokine stimulation is essential for a variety of immune responses… 
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