STAT1 protein, human

Known as: Transcription Factor ISGF-3 Components p91/p84, signal transducer and activator of transcription 1-alpha-beta protein, human, STAT91 protein, human 
Signal transducer and activator of transcription 1-alpha/beta (750 aa, ~87 kDa) is encoded by the human STAT1 gene. This protein plays a role in… (More)

Topic mentions per year

Topic mentions per year

1996-2018
0102019962018

Papers overview

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2005
2005
The V protein of simian virus 5 (SV5) facilitates the ubiquitination and subsequent proteasome-mediated degradation of STAT1… (More)
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Highly Cited
2004
Highly Cited
2004
STAT1 is a transcription factor that plays a crucial role in signaling by interferons (IFNs). In this study we demonstrated that… (More)
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Highly Cited
2002
Highly Cited
2002
Signal transducers and activators of transcription (STATs) reside in a latent state in the cytoplasm of the cell, but accumulate… (More)
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Highly Cited
2002
Highly Cited
2002
Sp3 is a ubiquitous transcription factor closely related to Sp1. Here we show that Sp3 is a target for SUMO modification in vivo… (More)
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Highly Cited
2001
Highly Cited
2001
Transcriptional induction by interferons requires the tyrosine and serine phosphorylation of STAT transcription factors. The N… (More)
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Highly Cited
1999
Highly Cited
1999
To replicate in vivo, viruses must circumvent cellular antiviral defense mechanisms, including those induced by the interferons… (More)
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Highly Cited
1999
Highly Cited
1999
STAT1 is an essential transcription factor for macrophage activation by IFN-gamma and requires phosphorylation of the C-terminal… (More)
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Highly Cited
1996
Highly Cited
1996
The JAK-STAT signaling pathway has been implicated in mediating biological responses induced by many cytokines. However… (More)
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Highly Cited
1996
Highly Cited
1996
Signal transducers and activators of transcription (STAT) proteins can be conditionally activated in response to epidermal growth… (More)
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Highly Cited
1996
Highly Cited
1996
STAT proteins (signal transducers and activators of transcription) are latent cytoplasmic transcription factors that are… (More)
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