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STAT1 protein, human

Known as: Transcription Factor ISGF-3 Components p91/p84, signal transducer and activator of transcription 1-alpha-beta protein, human, STAT91 protein, human 
Signal transducer and activator of transcription 1-alpha/beta (750 aa, ~87 kDa) is encoded by the human STAT1 gene. This protein plays a role in… 
National Institutes of Health

Related topics

Related topics

24 relations
DNA-Binding ProteinsEGF Signaling PathwayErythropoietin Signaling PathwayGenes, Regulator

Broader (1)

STAT1 protein

Papers overview

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2020
2020
Validation of STAT1 variants found in patients with primary immunodeficiencies and evaluation of the effect of JAK inhibition using an in vitro model.
Regulation of cellular responses to interferons, cytokines, growth factors and hormones is mediated by signal transducer and… 
2017
2017
Modulation of STAT1-Driven Transcriptional Activity by Histone Deacetylases.
The luciferase (LUC) reporter assay is commonly used to study gene expression at the transcriptional level. It is convenient… 
2017
2017
during Influenza and Bacterial Superinfection STAT 1 Is Required for Suppression of Type 17 Immunity
Influenza is an annual, global healthcare concern. Secondary bacterial pneumonia is a severe complication associated with primary… 
2016
2016
Expanded View Figures
  • 2016
  • Corpus ID: 265668128
Figure EV1. STAT1Y701F inhibits late STAT1-independent, STAT2/IRF9-dependent ISG expression in response to IFNb. A Expression of… 
2014
2014
Stat1 Negatively Regulates Immune-Mediated Injury with Anaplasma phagocytophilum Infection
Human granulocytic anaplasmosis (HGA) is caused by the obligate intracellular bacterium Anaplasma phagocytophilum. Our data… 
2014
2014
phagocytophilum Anaplasma Immune-Mediated Injury with Stat1 Negatively Regulates
Highly Cited
2011
Highly Cited
2011
Stat1 is a suppressor of ErbB2/Neu-mediated cellular transformation and mouse mammary gland tumor formation
The anti-tumor function of Stat1 as a regulator of innate immunity and tumor immune surveillance has been long studied and is… 
2004
2004
REQUIREMENT OF HISTONE DEACETYLASE ACTIVITY FOR SIGNALING BY STAT 1 Running title : HDAC and signaling by IFN γ
STAT1 is a transcription factor which plays a crucial role in signaling by IFNs. In this study we demonstrated that inhibitors of… 
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