Skip to search formSkip to main contentSkip to account menu

STAT1 protein

Known as: STAT1 Transcription Factor, Transcription Factor, STAT-91, STAT 91 Protein 
A signal transducer and activator of transcription that mediates cellular responses to INTERFERONS. Stat1 interacts with P53 TUMOR SUPPRESSOR PROTEIN… 
National Institutes of Health

Related topics

Related topics

12 relations
In BloodProcess of secretionSTAT1 geneSTAT5A protein, human

Narrower (1)

STAT1 protein, human

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2018
Highly Cited
2018
Translational control of tumor immune escape via the eIF4F–STAT1–PD-L1 axis in melanoma
Preventing the immune escape of tumor cells by blocking inhibitory checkpoints, such as the interaction between programmed death… 
Highly Cited
2017
Highly Cited
2017
Hematopoietic stem cell transplantation in patients with gain‐of‐function signal transducer and activator of transcription 1 mutations
Highly Cited
2016
Highly Cited
2016
Rapid decrease in hepatitis C viremia by direct acting antivirals improves the natural killer cell response to IFNα
Objective Chronic HCV infection is characterised by innate immune activation with increased interferon-stimulated genes (ISG… 
Highly Cited
2009
Highly Cited
2009
T‐helper 17 cells expand in multiple sclerosis and are inhibited by interferon‐β
T‐helper 1 (Th1) and Th17 lymphocytes are involved in experimental autoimmune encephalomyelitis, the model of multiple sclerosis… 
Highly Cited
2008
Highly Cited
2008
Crystal structure of unphosphorylated STAT3 core fragment.
Highly Cited
2005
Highly Cited
2005
Structural bases of unphosphorylated STAT1 association and receptor binding.
Review
2001
Review
2001
Imiquimod and resiquimod as novel immunomodulators.
Augmenting the host's natural immune response to viruses by the administration of exogenous cytokines such as interferon-alpha… 
Highly Cited
2001
Highly Cited
2001
Specificity of signaling by STAT1 depends on SH2 and C‐terminal domains that regulate Ser727 phosphorylation, differentially affecting specific target gene expression
Complete activation of signal transducer and activator of transcription 1 (STAT1) requires phosphorylation at both Y701 and a… 
Highly Cited
2000
Highly Cited
2000
Immune response in Stat2 knockout mice.
Highly Cited
1998
Highly Cited
1998
IFN-gamma induces cell growth inhibition by Fas-mediated apoptosis: requirement of STAT1 protein for up-regulation of Fas and FasL expression.
The mechanism by which IFN-gamma inhibits tumor cell growth has not been fully understood. Here we report that IFN-gamma up… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)