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STAT1 protein

Known as: STAT1 Transcription Factor, Transcription Factor, STAT-91, STAT 91 Protein 
A signal transducer and activator of transcription that mediates cellular responses to INTERFERONS. Stat1 interacts with P53 TUMOR SUPPRESSOR PROTEIN… 
National Institutes of Health

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In BloodProcess of secretionSTAT1 geneSTAT5A protein, human

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STAT1 protein, human

Papers overview

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2018
2018
Antitumour effects and mechanisms of action of the panHER inhibitor, dacomitinib, alone and in combination with the STAT3 inhibitor, S3I-201, in human sarcoma cell lines.
The 5-year survival rate for metastatic sarcoma is 16%. Although the phosphorylated human epidermal growth factor receptor (pEGFR… 
2014
2014
Selective inhibition of STAT1 reduces spinal cord injury in mice
2013
2013
A chimeric cyclic interferon-α2b peptide induces apoptosis by sequential activation of phosphatidylinositol 3-kinase, protein kinase Cδ and p38 MAP kinase.
2013
2013
Phosphorylation of STAT-1 Serine 727 Is Prolonged in HLA-B27-Expressing Human Monocytic Cells
A tissue antigen, HLA-B27, is strongly associated with a group of rheumatic diseases called spondyloarthritides. Despite the… 
2012
2012
Natural killer cell functional dichotomy: a feature of chronic viral hepatitis?
Natural killer (NK) cells are involved in innate immune responses to viral infections either via direct cytotoxicity which… 
Highly Cited
2009
Highly Cited
2009
Hepatic SOCS3 expression is strongly associated with non-response to therapy and race in HCV and HCV/HIV infection.
2009
2009
PKR-mediated degradation of STAT1 regulates osteoblast differentiation.
2008
2008
Effect of Jak2 kinase inhibition on Stat1 and Stat3 activation and apoptosis of tubular epithelial cells induced by ATP depletion/recovery.
BACKGROUND Apoptosis is involved in acute renal failure (ARF). Its exact mechanism still remains to be explored. The Jak-Stat… 
2006
2006
Rapamycin inhibits liver growth during refeeding in rats via control of ribosomal protein translation but not cap-dependent translation initiation.
We examined the role of the mammalian target of rapamycin (mTOR) in hepatic cell growth. To dissociate cell growth from cell… 
Highly Cited
2003
Highly Cited
2003
The Thanatophoric Dysplasia Type II Mutation Hampers Complete Maturation of Fibroblast Growth Factor Receptor 3 (FGFR3), Which Activates Signal Transducer and Activator of Transcription 1 (STAT1…
The K650E substitution in the fibroblast growth factor receptor 3 (FGFR3) causes constitutive tyrosine kinase activity of the… 
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