FAQ

STAT5A protein, human

Known as: signal transducer and activator of transcription 5A protein, human, STAT1, MGF protein, human 
Signal transducer and activator of transcription 5A (794 aa, ~91 kDa) is encoded by the human STAT5A gene. This protein is involved in… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1996-2018
05101519962018

Related topics

Related topics

21 relations
DNA-Binding ProteinsERBB Family Signaling PathwayERBB2 Signaling PathwayGenes, Regulator
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Broader (2)

STAT5 Transcription FactorTumor Suppressor Proteins

Related mentions per year

Related mentions per year

1946-2018
19401960198020002020
STAT5A protein, human
Signal Transduction
dna binding
Genes, Regulator
protein protein interaction
Transcriptional Regulation

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2011
2011
Productive Parvovirus B19 Infection of Primary Human Erythroid Progenitor Cells at Hypoxia Is Regulated by STAT5A and MEK Signaling but not HIFα
Human parvovirus B19 (B19V) causes a variety of human diseases. Disease outcomes of bone marrow failure in patients with high… (More)
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Highly Cited
2009
Highly Cited
2009
Development of mammary luminal progenitor cells is controlled by the transcription factor STAT5A.
Mammary alveologenesis is abrogated in the absence of the transcription factors STAT5A/5B, which mediate cytokine signaling. To… (More)
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2007
2007
STAT5A is epigenetically silenced by the tyrosine kinase NPM1-ALK and acts as a tumor suppressor by reciprocally inhibiting NPM1-ALK expression
Although STAT5A and STAT5B have some nonredundant functional properties, their distinct contributions to carcinogenesis are not… (More)
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2005
2005
The regulation of fatty acid synthase by STAT5A.
Growth hormone (GH) diminishes adipose tissue mass in vivo and decreases expression and activity of fatty acid synthase (FAS) in… (More)
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Highly Cited
2004
Highly Cited
2004
The ERBB4/HER4 receptor tyrosine kinase regulates gene expression by functioning as a STAT5A nuclear chaperone
In the lactating breast, ERBB4 localizes to the nuclei of secretory epithelium while regulating activities of the signal… (More)
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Highly Cited
2004
Highly Cited
2004
Constitutive Activation of STAT5A Promotes Human Hematopoietic Stem Cell Self-Renewal and Erythroid Differentiation
Activation of the transcription factor signal transducer and activator of transcription (STAT)5 is involved in various aspects of… (More)
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Highly Cited
2001
Highly Cited
2001
DNA binding specificity of different STAT proteins. Comparison of in vitro specificity with natural target sites.
STAT transcription factors are expressed in many cell types and bind to similar sequences. However, different STAT gene knock… (More)
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1999
1999
Differential effects of prolactin and src/abl kinases on the nuclear translocation of STAT5B and STAT5A.
In this study, DNA binding and tyrosine phosphorylation of STAT5A and STAT5B were compared with their subcellular localization… (More)
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1998
1998
A sequence of the CIS gene promoter interacts preferentially with two associated STAT5A dimers: a distinct biochemical difference between STAT5A and STAT5B.
Two distinct genes encode the closely related signal transducer and activator of transcription proteins STAT5A and STAT5B. The… (More)
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1996
1996
Granulocyte-macrophage colony-stimulating factor preferentially activates the 94-kD STAT5A and an 80-kD STAT5A isoform in human peripheral blood monocytes.
Granulocyte-macrophage colony-stimulating factor (GM-CSF) induces immediate effects in monocytes by activation of the Janus… (More)
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