SRD5A1 gene

Known as: steroid 5 alpha-reductase 1, 3-oxo-5-alpha-steroid 4-dehydrogenase 1, Steroid-5-Alpha-Reductase, Alpha Polypeptide 1 (3-Oxo-5 Alpha-Steroid Delta 4-Dehydrogenase Alpha 1) Gene 
This gene is involved in the metabolism of androgens.
National Institutes of Health

Papers overview

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2014
2014
The genotype distribution of two gene polymorphisms, previously associated with peripheral artery disease (PAD), has been… (More)
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2013
2013
11β-Hydroxyandrostenedione (11OHA4), which is unique to the adrenal, was first isolated from human adrenal tissue in the fifties… (More)
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Highly Cited
2011
Highly Cited
2011
In the majority of cases, advanced prostate cancer responds initially to androgen deprivation therapy by depletion of gonadal… (More)
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Highly Cited
2010
Highly Cited
2010
Androgen-deprivation therapy for prostate cancer (PC) eventually leads to castration-resistant PC (CRPC). Intratumoral androgen… (More)
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2008
2008
Although animal studies support the hypothesis that androgenic biological actions may affect experimental atherosclerosis… (More)
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2004
Highly Cited
2004
Recent evidence suggests that progesterone metabolites play important roles in regulating breast cancer. Previous studies have… (More)
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2004
2004
In men with a clinical diagnosis of benign prostatic hyperplasia (BPH), polytomous logistic regression analysis was conducted to… (More)
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2003
2003
BACKGROUND Steroid 5alpha-reductase 2 (SRD5A2) catalyzes the conversion of testosterone to the more potent androgen, DHT, in the… (More)
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2001
2001
Mice lacking steroid 5 alpha-reductase 1 and 2 were produced by gene targeting and breeding. Male mice without 5 alpha-reductase… (More)
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1999
1999
We previously reported lymphocyte expression of genes encoding enzymes required for steroid metabolism; however, only 17beta-HSD… (More)
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